Estimated delivery in United States, on Wednesday 10 Jul 2024
Product Information
Name:
Piperaquine Tetraphosphate
Controlled Product
Synonyms:
- 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis[7-chloroquinoline] Tetraphosphate
CAS:
Description:
Applications Piperaquine is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites. It is commonly used in combination with Dihydroartemisinin (D448360) for the treatment of multi-drug resistant falciparum malaria.
References Nguyen, T.M.T. et al.: Tap Chi Duoc Hoc, 57, 22 (2007); Song, J. et al.: Malaria J., 10, 231 (2011);
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
927.49
Formula:
C29H32Cl2N6•4H3PO4
Color/Form:
Neat
InChI:
InChI=1S/C29H32Cl2N6/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29/h2-9,20-21H,1,10-19H2
InChI key:
InChIKey=UCRHFBCYFMIWHC-UHFFFAOYSA-N
SMILES:
Clc1ccc2c(N3CCN(CCCN4CCN(c5ccnc6cc(Cl)ccc56)CC4)CC3)ccnc2c1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-P480050 Piperaquine Tetraphosphate
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