2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline

CAS: 60547-97-9

Ref. TR-P480500

Product Information

• Name: 2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline
• Synonyms: Prazosin Hydrochloride Imp. C (EP), Terazosin Hydrochloride Dihydrate Imp. C (EP),Doxazosin Mesilate Imp. G (EP), Prazosin Imp. C (EP), Terazosin Imp. C (EP), Terazosin USP Related Compound A, Terazosin USP RC A, 6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine, 4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)-, 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine, 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline, 2-(4-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline, 2-Piperazino-6,7-dimethoxy-4-quinazolinamine, 4-Amino-2-(1-piperazinyl)-6,7-dimethoxyquinazoline, 4-Amino-6,7-dimethoxy-2-(1-piperazinyl)quinazoline, Terazosin Related Compound A, Doxazosin Mesilate Impurity G, Prazosin Hydrochloride Impurity C, Terazosin Hydrochloride Dihydrate Impurity C, Doxazosin Impurity G, Prazosin Impurity C, Terazosin Impurity C, 2(1-Piperazinly)-4-amino-6,7-dimethoxyquinazoline, 4-Amino-2-(1-Piperazinyl)-6,7-Dimethoxy Quinazoline, 4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)-, 6,7-Dimethoxy-2-(Piperazin-1-Yl)Quinazolin-4-Amine

Description

Impurity Terazosin EP Impurity C
Applications 2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline (Terazosin EP Impurity C) is a metabolite of Prazosin. It is also an impurity arising in the synthesis of Terazosin (T105000).
References Bolognesi, M., et al.: J. Med. Chem., 44, 362 (2001), Shaw, Y., et al.: J. Med. Chem., 47, 4453 (2004), Erve, J., et al.: Drug Metab. Disposition, 35, 908 (2007), Cavalli, A., et al.: Bioorg. Med. Chem. Lett., 19, 3031 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 289.33
• Formula: C₁₄H₁₉N₅O₂
• Color/Form: White
• InChI: InChI=1S/C14H19N5O2/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18)
• InChI key: InChIKey=APKHJGDGWQDBGM-UHFFFAOYSA-N
• SMILES: COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC