3-(1-Piperazinyl)-1,2-benzisothiazole

CAS: 87691-87-0

Ref. TR-P480600

Product Information

• Name: 3-(1-Piperazinyl)-1,2-benzisothiazole
• Synonyms: 3-(Piperazin-1-yl)benzoisothiazole, N-(3-Benzisothiazolyl)piperazine, 1-(1,2-Benzisothiazol-3-yl)piperazine, Ziprasidone EP Impurity A, 1,2-Benzisothiazole, 3-(1-piperazinyl)-, 1-(1,2-Benzisothiazol-3-Yl)-Piperazine (Base), 1-(Benzisothiazol-3-yl)piperazine, 1-(Benzoisothiazol-3-yl)piperazine, 3-(1-Piperazinyl)-1,2-benzothiazole, 3-(1-Piperazizyl)-1,2-Benzisothiazole, 3-(Piperazin-1-Yl)Benzo[D]Isothiazole, 3-Piperazin-1-Yl-1,2-Benzisothiazole, 4-(1,2-Benzisothiazol-3-yl)-1-piperazine, Id 11614, Mj 14069, 4-(1,2-Benzisothiazol-3-yl)piperazine

Description

Impurity Ziprasidone EP Impurity A
Applications 3-(1-Piperazinyl)-1,2-benzisothiazole (Ziprasidone EP Impurity A) is a reagent used to synthesize Ziprasidone (Z485000, HCl salt, monohydrate), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Prakash, C., et al.: Brit. J. Clin. Pharmacol., 49, 35S (2000); Orjales, A., et al.: J. Med. Chem., 46, 5512 (2003); Graham, J., et al.: Bioorg. Med. Chem. Lett., 18, 489 (2008); Bench, C.J., et al.: Psychopharmacology, 112, 308 (1993), Goldstein, J.M.: Exp. Opin. Invest. Drugs, 4, 291 (1995)

• Brand: TRC

Chemical properties

• Molecular weight: 219.31
• Formula: C₁₁H₁₃N₃S
• Color/Form: Neat
• InChI: InChI=1S/C11H13N3S/c1-2-4-10-9(3-1)11(13-15-10)14-7-5-12-6-8-14/h1-4,12H,5-8H2
• InChI key: InChIKey=KRDOFMHJLWKXIU-UHFFFAOYSA-N
• SMILES: c1ccc2c(N3CCNCC3)nsc2c1