(5a)-Pregnane-3,20-dione

CAS: 566-65-4

Ref. TR-P705150

Product Information

• Name: (5a)-Pregnane-3,20-dione
• Synonyms: 3,20-Allopregnanedione, Pregnane-3,20-dione, (5α)-, 5α-Pregnane-3,20-dione (8CI), 5α-Pregnanedione (7CI), 3,20-Allopregnanedione, 3,20-Dioxo-5α-pregnane, 5α-Dihydro-P4, 5α-Dihydroprogesterone, NSC 18319, (+)-(5α)-Pregnane-3,20-dione, 5-Alpha-Dihydroprogesterone, 5-Alpha-Pregnane-3,20-Dione, 5-Α-Pregnane-3,20-Dione, 5-Α-Pregnano-3,20-Diona, 5-α-Pregnan-3,20-dion, 5A-pregnane-3-20-dione-allo, 5α-Pregnanedione, Nsc 18319, Pregnan-3,20-dione, Pregnane-3,20-dione, (5α)-
• CAS: 566-65-4

Description

Applications (5α)-Pregnane-3,20-dione exerts neuroprotective effects in chronic autoimmune encephalomyelitis (EAE). The neuroactivity of the steroid acts as a therapeutic agent for multiple sclerosis.
References Caruso, D. et al.: J. Neuroendocrinol., 24, 851 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 316.48
• Formula: C₂₁H₃₂O₂
• Color/Form: Off-White
• InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14,16-19H,4-12H2,1-3H3/t14-,16-,17+,18-,19-,20-,21+/m0/s1
• InChI key: InChIKey=XMRPGKVKISIQBV-BJMCWZGWSA-N
• SMILES: CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C