Acetamide Baricitinib Impurity
CAS: 2271228-51-2
Ref. TR-P852225
| 1mg | Discontinued | ||
| 5mg | Discontinued | ||
| 10mg | Discontinued |
Product Information
Name:
Acetamide Baricitinib Impurity
Synonyms:
- 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetamide
- 2-(3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetamide
Description:
Applications 2-(3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetamide is an impurity of Baricitinib (B118690), which is a JAK1 and JAK2 inhibitor and has been studied as a promising treatment for rheumatoid arthritis.
References Dasari, S., et. al.: Russ. J. Org., 55, 1569 (2019);Zhang, F., et. al.: Faming Zhuanli Shenqing 11pp. Patent (2018), CN 108976233 A 20181211;Greenwald, L., et. al.: Int. J. Clin. Rheumatol., 6, 401 (2011); Fridman, J., et. al.: J. Immunol., 184, 5298 (2010);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
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Chemical properties
Molecular weight:
389.43
Formula:
C16H19N7O3S
Color/Form:
Off-White To Light Yellow
InChI:
InChI=1S/C16H19N7O3S/c1-2-27(25,26)22-8-16(9-22,5-13(17)24)23-7-11(6-21-23)14-12-3-4-18-15(12)20-10-19-14/h3-4,6-7,10H,2,5,8-9H2,1H3,(H2,17,24)(H,18,19,20)
InChI key:
InChIKey=GKBJBCCNXISYKV-UHFFFAOYSA-N
SMILES:
CCS(=O)(=O)N1CC(CC(N)=O)(n2cc(-c3ncnc4[nH]ccc34)cn2)C1
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