Raloxifene 4’-Beta-D-Glucuronide Lithium Salt

CAS: 182507-22-8

Ref. TR-R100021

Product Information

• Name: Raloxifene 4’-Beta-D-Glucuronide Lithium Salt
• Synonyms: 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-β-D-glucopyranosiduronic Acid Lithium Salt, (4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy-D4]benzoyl]benzo[b]thien-2-yl]phenyl-D-glucopyranosiduronic acid), 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy-d4]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic Acid, 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid, 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-D-glucopyranosiduronicacid, 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic Acid, Raloxifene-D4-4'-Glucuronide, β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-[6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl
• CAS: 182507-22-8

Description

Stability Hygroscopic
Applications Raloxifene 4’-Glucuronide Lithium Salt is a metabolite of Raloxifene (R099995), a nonsteroidal estrogen receptor mixed agonist/antagonist.
References Dodge, J., et al.: Bioorg. Med. Chem. Lett., 7, 993 (1997); Jeong, E., et al.: Drug Metab. Dispos., 33, 785 (2005); Trontelj, J., et al.: Pharmacol. Res., 52, 334 (2005); Oswald, S., et al.: Clin. Pharmacol. Ther., 79 206 (2006)

• Brand: TRC

Chemical properties

• Molecular weight: 655.64
• Formula: C₃₄H₃₄LiNO₁₀S
• Color/Form: Neat
• InChI: InChI=1S/C34H35NO10S.Li/c36-21-8-13-24-25(18-21)46-32(20-6-11-23(12-7-20)44-34-30(40)28(38)29(39)31(45-34)33(41)42)26(24)27(37)19-4-9-22(10-5-19)43-17-16-35-14-2-1-3-15-35;/h4-13,18,28-31,34,36,38-40H,1-3,14-17H2,(H,41,42);/q;+1/p-1/t28-,29-,30+,31-,34+;/m0./s1
• InChI key: InChIKey=AKGXZWGDHSMZHM-REJGPQDISA-M
• SMILES: [Li]OC(=O)[C@H]1O[C@@H](Oc2ccc(-c3sc4cc(O)ccc4c3C(=O)c3ccc(OCCN4CCCCC4)cc3)cc2)[C@H](O)[C@@H](O)[C@@H]1O