Rifamycin O

CAS: 14487-05-9

Ref. TR-R508190

Product Information

• Name: Rifamycin O
• Synonyms: Rifamycin, 4-O-(carboxymethyl)-1-deoxy-1,4-dihydro-4-hydroxy-1-oxo-, ?-lactone, Acetic acid, [(1,2,6,9-tetrahydro-5,9,17,19,21-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,6,11-trioxo-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-9-yl)oxy]-, ?-lactone, 21-acetate (7CI), Rifomycin O (6CI), Spiro[1,3-dioxolane-2,9'(6'H)-[2,7](epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan]-1',4,6',11'(2'H)-tetrone, 5',17',19',21'-tetrahydroxy-23'-methoxy-2',4',12',16',18',20',22'-heptamethyl-, 21'-acetate (8CI), Spiro[1,3-dioxolane-2,9'(6'H)-[2,7](epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan], rifamycin deriv., NSC 182391, Rifaximin Imp F (EP)
• CAS: 14487-05-9

Description

Impurity Rifaximin EP Impurity F
Applications Rifamycin O (Rifaximin EP Impurity F) is a Rifaximin intermediate.
References Vohra, R., et al.: Biotechnol. Lett., 11, 851 (1989), Bacchi, A., et al.: J. Med. Chem., 41, 2319 (1998),

• Brand: TRC

Chemical properties

• Molecular weight: 753.79
• Formula: C₃₉H₄₇NO₁₄
• Color/Form: Neat
• InChI: InChI=1S/C39H47NO14/c1-17-11-10-12-18(2)37(48)40-24-15-39(51-16-26(42)53-39)29-27(33(24)46)32(45)22(6)35-28(29)36(47)38(8,54-35)50-14-13-25(49-9)19(3)34(52-23(7)41)21(5)31(44)20(4)30(17)43/h10-15,17,19-21,25,30-31,34,43-45H,16H2,1-9H3,(H,40,48)/b11-10-,14-13-,18-12-/t17-,19+,20+,21+,25-,30-,31+,34+,38-,39?/m0/s1
• InChI key: InChIKey=RAFHKEAPVIWLJC-PQVBCCSKSA-N
• SMILES: CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(c3C2=O)C2(C=C(NC(=O)/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C4=O)OCC(=O)O2