Product Information
- N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide
- Omaveloxolone
Applications Synthetic triterpenoids, such as RTA 408, are antioxidant inflammation modulator (AIM) that can inhibit tumor cell growth and metastasis via oncogenic signaling pathways. RTA 408 is an anticancer, anti-inflammatory, and antioxidant agent that protects human retinal pigment epithelial cells against H2O2-induced cell injury by activating NF-E2-related factor 2.
References Liu, X., et al.: Redox Biol. 8, 98 (2016); Probst, B. L., et al.: PLoS One. 10, e0122942 (2015)
Chemical properties
Technical inquiry about: TR-R700990 RTA 408
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