Scopine Di(2-thienylglycolate)

CAS: 136310-64-0

Ref. TR-S199965

Product Information

• Name: Scopine Di(2-thienylglycolate)
• Synonyms: 2-Thiopheneacetic acid, alpha-hydroxy-alpha-2-thienyl-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, (1alpha,2beta,4beta,5alpha,7beta)-, (1alpha,2beta,4beta,5alpha,7beta)-7-[(Hydroxydi(2-thienyl)acetyl)oxy]-9-methyl-3-oxa-9-azatricyclo[3.3.1.0]nonane, Di(2-thienyl)glycolic acid scopine ester, Dithienylglycolic acid scopine ester, N-Demethyl tiotropium, Scopine hydroxydi(2-thienyl)acetate, 2-Thiopheneacetic acid, alpha-hydroxy-alpha-2-thienyl-, (1alpha,2beta,4beta,5alpha,7beta)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, Tiotropium Bromide Monohydrate Imp B (EP), Tiotropium Bromide Monohydrate Impurity B, Tiotropium Impurity B, (1α,2β,4β,5α,7β)-7-[(Hydroxydi(2-thienyl)acetyl)oxy]-9-methyl-3-oxa-9-azatricyclo[3.3.1.0]nonane, (1α,2β,4β,5α,7β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl α-hydroxy-α-2-thienyl-2-thiopheneacetate, 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, (1α,2β,4β,5α,7β)-, 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.02,4]Non-7-Yl Hydroxy(Dithiophen-2-Yl)Acetate, Scopine di(2-thienylglycolate), Scopine-2,2-Dithienyl Glycolate, 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, (1α,2β,4β,5α,7β)-, 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, (1α,2β,4β,5α,7β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl α-hydroxy-α-2-thienyl-2-thiopheneacetate

Description

Impurity Tiotropium EP Impurity B
Applications Scopine Di(2-thienylglycolate) (Tiotropium EP Impurity B) is a precursor to Tiotropium Bromide.
References Buchwald, P., et al.: Pharmazie., 55, S210 (2000),

• Brand: TRC

Chemical properties

• Molecular weight: 377.48
• Formula: C₁₈H₁₉NO₄S₂
• Color/Form: Neat
• InChI: InChI=1S/C18H19NO4S2/c1-19-11-8-10(9-12(19)16-15(11)23-16)22-17(20)18(21,13-4-2-6-24-13)14-5-3-7-25-14/h2-7,10-12,15-16,21H,8-9H2,1H3/t10-,11-,12+,15-,16+
• InChI key: InChIKey=VPJFFOQGKSJBAY-FDAWXEHDSA-N
• SMILES: CN1[C@H]2C[C@H](OC(=O)C(O)(c3cccs3)c3cccs3)C[C@@H]1[C@H]1O[C@@H]21