D-erythro-Sphingosine (synthetic)

CAS: 123-78-4

Ref. TR-S681000

Product Information

• Name: D-erythro-Sphingosine (synthetic)
• Synonyms: (E,2S,3R)-2-aminooctadec-4-ene-1,3-diol, (-)-<span class="text-smallcaps">D</span>-erythro-Sphingosine, (-)-D-erythro-Sphingosine, (2S,3R)-Sphingosine, (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol, (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, (4E)-2-aminooctadec-4-ene-1,3-diol, (4E)-Sphingenine, (E)-2-Amino-4-octadecan-1,3-diol, 2-Aminooctadec-4-en-1,3-diol, 4-Octadecene-1,3-diol, 2-amino-, (2S,3R,4E)-, 4-Octadecene-1,3-diol, 2-amino-, (E)-<span class="text-smallcaps">D</span>-erythro-, 4-Octadecene-1,3-diol, 2-amino-, (E)-D-erythro-, 4-Octadecene-1,3-diol, 2-amino-, (R-(R*,S*-(E)))-, 4-Sphingenine, 4-trans-Sphingenine, <span class="text-smallcaps">D</span>-(+)-erythro-4-trans-Sphingenine, <span class="text-smallcaps">D</span>-Sphingosine, <span class="text-smallcaps">D</span>-erythro-C₁₈-Sphingosine, C18-Sphingosine, C₁₈-Sphingosine, Ccris 6899, D-(+)-erythro-4-trans-Sphingenine, D-Sphingosine, D-erythro-C18-Sphingosine, Erythrosphingosine, Sphingenine, Sphingosine, erythro-4-Sphingenine, erythro-C18-Sphingosine, erythro-C₁₈-Sphingosine, trans-4-Sphingenine
• CAS: 123-78-4

Description

Stability Store in freezer
Applications Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine.
References Yoon, C., et al.: Mol. Cancer Res., 7, 361 (2009), Giussani, P., et al.: J. Biol. Chem., 284, 5088 (2009), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009), Satoh, Y., et al.: J. Biochem., 145, 31 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 299.49
• Formula: C₁₈H₃₇NO₂
• Color/Form: White Solid
• InChI: InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
• InChI key: InChIKey=WWUZIQQURGPMPG-KRWOKUGFSA-N
• SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO