Succinimidyl-6-(biotinamido) Hexanoate

CAS: 72040-63-2

Ref. TR-S690250

Product Information

• Name: Succinimidyl-6-(biotinamido) Hexanoate
• Synonyms: Enzotin, EZ-Link NHS-LC-Biotin, N-[5-(Succinimidyloxycarbonyl)pentyl]biotin Amide, N-Hydroxysuccinimidyl 6-(Biotinamido)hexanoate, N-Hydroxysuccinimidyl Biotinamidocaproate, B 1582, NHS-LC-Biotin, 6-[(Biotinyl)amino]hexanoic Acid N-Hydroxysuccinimide Ester, 5-(N-Succinimidyloxycarbonyl)pentyl d-Biotinamide, B 1582, (+)-Biotinamidocaproate N-hydroxysuccinimidyl ester, 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]hexahydro-2-oxo-, (3aS,4S,6aR)-, 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]hexahydro-2-oxo-, [3aS-(3aα,4β,6aα)]-, 5-(N-Succinimidyloxycarbonyl)pentyl d-biotinamide, 6-[(Biotinyl)amino]hexanoic acid N-hydroxysuccinimide ester, <span class="text-smallcaps">D</span>-(+)-Biotinyl-ε-aminocaproic acid N-hydroxysuccimide ester, Biotin-LC-NHS, Biotin-X, SE, Biotinamidocaproate N-hydroxysuccinimide ester, Biotinamidohexanoic acid N-hydroxysuccinimide ester, Hexanoic acid, 6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester, N-(+)-Biotinyl-6-aminocaproic acid N-succinimidyl ester, N-Hydroxysuccinimidyl 6-(biotinamido)hexanoate, N-Hydroxysuccinimidyl biotinamidocaproate, N-Succinimidyl N-biotinyl-6-aminocaproate, N-[5-(Succinimidyloxycarbonyl)pentyl]biotin amide, N-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, N-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
• CAS: 72040-63-2

Description

Stability Moisture Sensitive
Applications Succinimidyl-6-(biotinamido) Hexanoate is a biotinylation reagent incorporating an aminocaproyl “spacer”. This can reduce the steric hindrance in binding avidin to some biotinylated compounds when used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin Capture System. This system avoids the direct interaction of a captured antibody with solid surfaces, such as plastics, which may reduce antigenicity. It has also been used to enhance the detection of DNA on nitrocellulose. Has also been used as a cell surface labelling reagent
References Hofmann, K., et al.: Biochemistry, 21, 978 (1982); Leary, J.J., et al.: P. Natl. Acad. Sci. USA, 80, 4045, (1983); Suter, M., et al.: Immunology Letters, 13, 313 (1986); Gretch, D.R., et al.: Anal. Biochem., 163, 270 (1987), Burgess, T.L., et al.: J. Biol. Chem., 269 (32), 19188 (1995), Schumacher, T.N.M., et al.: Science, 271, 1854 (1996)

• Brand: TRC

Chemical properties

• Molecular weight: 454.54
• Formula: C₂₀H₃₀N₄O₆S
• Color/Form: Off White Crystalline Powder
• InChI: InChI=1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1
• InChI key: InChIKey=UVGHPGOONBRLCX-NJSLBKSFSA-N
• SMILES: O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NCCCCCC(=O)ON1C(=O)CCC1=O