Sulindac Sulfone-d6

CAS: 59973-80-7

Ref. TR-S699227

Product Information

• Name: Sulindac Sulfone-d6
• Synonyms: (Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid-d6, Aptosyn-d6, Exisulind-d6, FGN 1-d6, Prevatec-d6, (1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (1Z)-, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (Z)-, Aposulind, Aptosyn, Exisulind, Fgn-1, Prevatac(former Brand Name), Prevatec, Sulindac sulfone, cis-5-Fluoro-2-methyl-1-[p-methylsulfonylbenzylidenyl]indene-3-acetic acid
• CAS: 59973-80-7

Description

Applications Labelled analogue of Sulindac Sulfone, an active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis.
References Piazza, G.A. et al.: Cancer Res., 55, 3310 (1995);

• Brand: TRC

Chemical properties

• Molecular weight: 378.45
• Formula: C₂₀H₁₁D₆FO₄S
• Color/Form: Light Yellow to Yellow Solid
• InChI: InChI=1S/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-/i2D3,9D,11D2
• InChI key: InChIKey=MVGSNCBCUWPVDA-NUJVTHJYSA-N
• SMILES: [2H]/C(=C1\C(C)=C(C([2H])([2H])C(=O)O)c2cc(F)ccc21)c1ccc(S(=O)(=O)C([2H])([2H])[2H])cc1