Temozolomide

CAS: 85622-93-1

Ref. TR-T017775

Product Information

• Name: Temozolomide
• Synonyms: 3-Methyl-4-oxo-8-imidazolo[5,1-d][1,2,3,5]tetrazinecarboxamide, 3-Methyl-8-carbamoylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, 8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, CCRG 81045, M and B 39831, MB 39831, Methazolastone, NSC 362856, Sch 52365, Temodal, Temodar, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-, 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3-Methyl-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide, 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide, 3-Methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide, 3-Methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide, 4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide, Ccrg 81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-, Mb 39831, T 2577, Temomedac, Temozolamide

Description

Applications Imidazotetrazine alkylating agent. An antineoplastic.
References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997), Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999), Hait, W., et al.: Cancer Res., 69, 1263 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 194.15
• Formula: C₆H₆N₆O₂
• Color/Form: White
• InChI: InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)
• InChI key: InChIKey=BPEGJWRSRHCHSN-UHFFFAOYSA-N
• SMILES: Cn1nnc2c(C(N)=O)ncn2c1=O