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Product Information
Name:
Tenofovir Disoproxil Fumarate
Controlled Product
Synonyms:
- 5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic acid 1,9-bis(1-methylethyl) ester 5-oxide (2E)-2-butenedioate (1:1)
- 5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic acid bis(1-methylethyl) ester 5-oxide (2E)-2-butenedioate (1:1)
- (R)-5-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic acid bis(1-methylethyl) ester 5-oxide (E)-2-butenedioate (1:1)
- GS 4331-05
- PMPA Prodrug
- Tenfovir disoproxil fumarate
- Tenofovir DF
- Virea
- Viread
- BPPF
- See more synonyms
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (R)-, (E)-2-butenedioate (1:1)
- 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarate
- Gs 4331-05
- Tenofovir Dipivoxil Fumarate
- Tenofovir Disproxil Fumarate
- bis({[(1-methylethoxy)carbonyl]oxy}methyl) {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonate (2E)-but-2-enedioate
CAS:
Description:
Applications Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
635.51
Formula:
C23H34N5O14P
Color/Form:
Neat
InChI:
/m1./s1, InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24, 5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22), 1-2H,(H,5,6)(H,7,8)/b, 2-1+/t14-
InChI key:
InChIKey=WPIDCVJSAMWXHR-KPJQVXLKSA-N
SMILES:
CC(C)C1(C)CCOP(=O)(CO[C@H](C)Cn2cnc3c(N)ncnc32)OC1.O=C(O)/C=C/C(=O)O.O=C(O)O.O=C(O)O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-T018505 Tenofovir Disoproxil Fumarate
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