Product Information
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid
- 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-
- 1-ethyl 9-(1-methylethyl) ester
- 5-oxide
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide
Stability Hygroscopic
Applications Tenofovir Disopropyl Ethyl Diester is an impurity of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),
Chemical properties
Technical inquiry about: TR-T018530 Tenofovir Isopropyl Ethyl Diester
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