N,N',N'',N'''Tetraacetylglycoluril

CAS: 10543-60-9

Ref. TR-T282350

Product Information

• Name: N,N',N'',N'''Tetraacetylglycoluril
• Synonyms: 1,3,4,6-Tetraacetyltetrahydro-imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-Tetraacetylglycoluril, Tetraacetylglyclouril, Tetraacetylglycoluril, 1,3,4,6-Tetraacetyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione, 1,3,4,6-Tetraacetyl-tetrahydro-imidazo[4,5-d]imidazole-2,5-dione, 1,3,4,6-Tetraacetylimidazo [4,5-d] imidazole-2,5-[1H,3H]-dione, 1,3,4,6-tetraacetyltetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 5-D]Imidazole-2,5(1H,3H)-Dione,1,3,4,6-Tetraacetyltetrahydro-Imidazo[, 5-d]imidazole-2,5(1H,3H)-dione,1,3,4,6-tetraacetyltetrahydro-Imidazo[4, Glycoluril, 1,3,4,6-tetraacetyl-, Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-tetraacetyltetrahydro-, N,N',N'',N'''-Tetraacetylacetyleneurea, N,N′,N′′,N′′′Tetraacetylglycoluril, Perhydro-1,3,4,6-Tetraacetylimidazo(4,5-D)Imidazole-3,5-Dione, Tetraacetyl glycoluril

Description

Applications N,N',N'',N'''Tetraacetylglycoluril is the tetraacetylated derivative of Glycoluril (G645900); a reagent used in the synthesis of acyclic cucurbit[n]uril molecular containers which can enhance the solubility and bioactivity of poorly soluble pharmaceuticals. Glycoluril is also used as a reagent in the synthesis of cucurbit[7]uril containers for targeted delivery of oxaliplatin to cancer cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ma, D., et al.: Nature Chem., 4, 503 (2012); Cao, L., et al.: Angew. Chem. Int. Edit., 52, 12033 (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 310.26
• Formula: C₁₉H₂₃FN₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C19H23FN2O2/c1-13(19(2,3)4)22-18(23)15-8-9-17(21-11-15)24-12-14-6-5-7-16(20)10-14/h5-11,13H,12H2,1-4H3,(H,22,23)/t13-/m1/s1
• InChI key: InChIKey=VOYBJCDMLJODRK-CYBMUJFWSA-N
• SMILES: C[C@@H](NC(=O)c1ccc(OCc2cccc(F)c2)nc1)C(C)(C)C