N,N',N'',N'''Tetraacetylglycoluril-d12

CAS: 10543-60-9

Ref. TR-T282352

Product Information

• Name: N,N',N'',N'''Tetraacetylglycoluril-d12
• Synonyms: 1,3,4,6-Tetraacetyltetrahydro-imidazo[4,5-d]imidazole-2,5(1H,3H)-dione-d12, 1,3,4,6-Tetraacetylglycoluril-d12, Tetraacetylglyclouril-d12, Tetraacetylglycoluril-d12, 1,3,4,6-Tetraacetyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione, 1,3,4,6-Tetraacetyl-tetrahydro-imidazo[4,5-d]imidazole-2,5-dione, 1,3,4,6-Tetraacetylglycoluril, 1,3,4,6-Tetraacetylimidazo [4,5-d] imidazole-2,5-[1H,3H]-dione, 1,3,4,6-tetraacetyltetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 5-D]Imidazole-2,5(1H,3H)-Dione,1,3,4,6-Tetraacetyltetrahydro-Imidazo[, 5-d]imidazole-2,5(1H,3H)-dione,1,3,4,6-tetraacetyltetrahydro-Imidazo[4, Glycoluril, 1,3,4,6-tetraacetyl-, Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-tetraacetyltetrahydro-, N,N',N'',N'''-Tetraacetylacetyleneurea, N,N′,N′′,N′′′Tetraacetylglycoluril, Perhydro-1,3,4,6-Tetraacetylimidazo(4,5-D)Imidazole-3,5-Dione, Tetraacetyl glycoluril, Tetraacetylglyclouril, Tetraacetylglycoluril

Description

Applications N,N',N'',N'''Tetraacetylglycoluril-d12 is the isotope labelled analog of N,N',N'',N'''Tetraacetylglycoluril (T282350); the tetraacetylated derivative of Glycoluril (G645900) which is a reagent used in the synthesis of acyclic cucurbit[n]uril molecular containers which can enhance the solubility and bioactivity of poorly soluble pharmaceuticals. Glycoluril is also used as a reagent in the synthesis of cucurbit[7]uril containers for targeted delivery of oxaliplatin to cancer cells.
References Ma, D., et al.: Nature Chem., 4, 503 (2012); Cao, L., et al.: Angew. Chem. Int. Edit., 52, 12033 (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 322.34
• Formula: C₁₂H₂D₁₂N₄O₆
• Color/Form: Neat
• InChI: InChI=1S/C9H7FO2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-2,5H,3-4H2
• InChI key: InChIKey=SWBBIJZMIGAZHW-UHFFFAOYSA-N
• SMILES: O=C1CCOc2ccc(F)cc21