1,2,4,5-Tetrahydro-3H-1,4-benzodiazepin-3-one
CAS: 168080-43-1
Ref. TR-T293010
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
- 2,3,4,5-Tetrahydro-1H-1,4-benzodiazepin-3-one
- 3H-Benzo[e][1,4]diazepin-3-one
- 1,2,4,5-Tetrahydro-Benzo[E][1,4]Diazepin-3-One
Applications These compounds have stimulating activity on type 2 arginine vasopressin receptor (V2 receptor) and are useful as preventive or therapeutic agents for diabetes insipidus, night pollakiuria, night enuresis, overactive bladder, haemophilia, or Von Willebrand’s disease.
References Stromblad, S., et al.: Chem. Biol., et al.: 3, 881 (1996), Kireeva, M., et al.: J. Biol. Chem., 273, 3090 (1998), Nakamura, I., et al.: J. Cell. Sci.,112, 3985 (1999), Ward, K., et al.: Drug Metab. Dispos., 27, 1232 (1999), Miller, W., et al.: J. Med. Chem., 43, 22 (2000)