Tetrahydro-a-(1-naphthalenylmethyl)-2-furanpropanoic Acid

CAS: 25379-26-4

Ref. TR-T293510

Product Information

• Name: Tetrahydro-a-(1-naphthalenylmethyl)-2-furanpropanoic Acid
• Synonyms: LS 74,Tetrahydro-alpha-(1-naphthalenylmethyl)-2-furanpropanoic acid, 2-Furanpropionic acid, tetrahydro-alpha-(1-naphthylmethyl)- (7CI,8CI), Tetrahydro-alpha-(1-naphthylmethyl)-2-furanpropionic acid, alpha-(1-Naphthalenylmethyl)-3-tetrahydrofuran-2-propionic acid, 1-(2-Tetrahydrofuryl)-3-(1-Naphthyl)Propane-2-Carboxylic Acid, 1-(Tetrahydro-2-Furyl)-3-(1-Naphthyl) Propane-2-Carboxylic Acid, 1-(Tetrahydro-2-furyl)-3-(1-naphthyl)propane-2-carboxylicacid, 2-(Naphthalen-1-ylmethyl)-3-(oxolan-2-yl)propanoic acid, 2-Furanpropanoic acid, tetrahydro-α-(1-naphthalenylmethyl)-, 2-Furanpropionic acid, tetrahydro-α-(1-naphthylmethyl)-, 3-(Naphthalen-1-Yl)-2-(Tetrahydrofuran-2-Ylmethyl)Propanoic Acid, Ls 74, Naphthidrofurylic acid, Naphthylmethyltetrahydrofurfurylpropanoic acid, Tetrahydro-alpha-(1-naphthylmethyl)furan-2-propionic acid, Tetrahydro-α-(1-naphthalenylmethyl)-2-furanpropanoic acid, Tetrahydro-α-(1-naphthylmethyl)-2-furanpropionic acid, α-(1-Naphthalenylmethyl)-3-tetrahydrofuran-2-propionic acid

Description

Applications Tetrahydro-α-(1-naphthalenylmethyl)-2-furanpropanoic Acid is a Nafronyl (N215000) derivative. Nafronyl is a selective inhibitor of serotonin receptors. Nafronyl is a vasodilator used in the treatment of intermittent claudication.
References Fontaine, et al.: Chim. Ther., 4, 44 (1969); Bessin, P., et al.: Eur. J. Med. Chem., 10, 291 (1975); Clyne, C.A., et al.: Br. J. Surg., 67, 347 (1980)

• Brand: TRC

Chemical properties

• Molecular weight: 284.35
• Formula: C₁₈H₂₀O₃
• Color/Form: Neat
• InChI: InChI=1S/C18H20O3/c19-18(20)15(12-16-8-4-10-21-16)11-14-7-3-6-13-5-1-2-9-17(13)14/h1-3,5-7,9,15-16H,4,8,10-12H2,(H,19,20)
• InChI key: InChIKey=VEJYFDMNWGFBCT-UHFFFAOYSA-N
• SMILES: O=C(O)C(Cc1cccc2ccccc12)CC1CCCO1