Product Information
- 5alpha-Estran-17alpha-ethinyl-3alpha,17beta-diol
- 19-Norpregn-20-yne-3,17-diol
- (3a,5a,17a)-
- 19-Nor-5a,17a-pregn-20-yne-3a,17-diol (8CI)
- 17a-Ethynyl-5a-estrane-3a,17ß-diol
- 17a-Ethynyl-5a-oestrane-3a,17ß-diol
Applications A 3α-metabolite of progesterone receptor agonist Norethindrone (N676000) that acts as an estrogen receptor in osteoblastic cells. It also has novel nongenomic endothelium-independent vaso-relaxing effects.
References Lemus, A.E. et al.: J. Endocrinol., 200, 199 (2009); Perusquia, M. et al.: Eur. J. Pharmacol., 475, 161 (2003); Blom, M.J. et al.: Drug Metab. Disp., 29, 976 (2001);
Chemical properties
Technical inquiry about: TR-T294135 3alpha,5alpha-Tetrahydronorethisterone
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