Tetrahydro Erlotinib

CAS: 299912-61-1

Ref. TR-T294720

Product Information

• Name: Tetrahydro Erlotinib
• Synonyms: N-(3-Ethylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine

Description

Applications Tetrahydro Erlotinib is an impurity of Erlotinib (E625000, HCl); a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor and antineoplastic agent.
References Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997); Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001); Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004); Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005)

• Brand: TRC

Chemical properties

• Molecular weight: 397.47
• Formula: C₂₂H₂₇N₃O₄
• Color/Form: Off-White Solid
• InChI: InChI=1S/C22H27N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h5-7,12-15H,4,8-11H2,1-3H3,(H,23,24,25)
• InChI key: InChIKey=NUQUOVYZADJDTI-UHFFFAOYSA-N
• SMILES: CCc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1