1,2,3,4-Tetrahydro Staurosporin
CAS: 220038-19-7
Ref. TR-T295700
| 1mg | 654.00 € | ||
| 500µg | 374.00 € | ||
| 2500µg | 1,477.00 € |
Estimated delivery in United States, on Friday 31 May 2024
Product Information
Name:
1,2,3,4-Tetrahydro Staurosporin
Synonyms:
- (9S,10R,11R,13R)-2,3,10,11,12,13,15,16,17,18-Decahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
- AFN 941
CAS:
Description:
Applications Staurosporine derivative for use as isoenzyme PKCα inhibitors and anticancer agents.
References Pollack, V., et al.: J. Pharmacol. Exp. Ther., 291, 739 (1999), Barker, A., et al.: Bioorg. Med. Chem. Lett., 11, 1911 (2001), Brignola, P., et al.: J. Biol. Chem., 277, 1576 (2002), Amann, J., et al.: Cancer Res., 65, 226 (2005), Zhang, X., et al.: Cell, 125, 1137 (2006),
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
466.53
Formula:
C28H30N4O3
Color/Form:
Pale Yellow to Light Yellow Solid
InChI:
InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
InChI key:
InChIKey=KIZWKTROWIIMNN-FYTWVXJKSA-N
SMILES:
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6c(n2c5c31)CCCC6)C(=O)NC4
MDL:
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