Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
Trametinib (DMSO Solvate)
Controlled Product
Synonyms:
- Acetamide
- N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-
- compd. with 1,1'-sulfinylbis[methane] (1:1)
- GSK 1120212B
- Trametinib dimethyl sulfoxide
- GSK 1120212B
- Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1′-sulfinylbis[methane] (1:1)
- Gsk 1120212B
- Trametinib DMSO
CAS:
Description:
Applications Trametinib (DMSO Solvate) is a highly potent and selective MEK inhibitor with significant antitumor activity.
References Abe, H., et al.: ACS Med. Chem. Lett., 2, 320 (2011)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
693.53
Formula:
C28H29FIN5O5S
Color/Form:
White
InChI:
InChI=1S/C26H23FIN5O4.C2H6OS/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34;1-4(2)3/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34);1-2H3
InChI key:
InChIKey=OQUFJVRYDFIQBW-UHFFFAOYSA-N
SMILES:
CC(=O)Nc1cccc(-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c32)c1.CS(C)=O
MDL:
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Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-T314310 Trametinib (DMSO Solvate)
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