Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride
CAS: 1247119-33-0
Ref. TR-T344296
| 50mg | 1,059.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
Product Information
Name:
Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride
Controlled Product
Synonyms:
- Carbamic acid
- N-[(1R,4R)-4-amino-5-phenyl-1-(phenylmethyl)pentyl]-
- 5-thiazolylmethyl ester
- hydrochloride (1:1)
- Thiazol-5-ylmethyl N-((1R,4R)-4-Amino-1-benzyl-5-phenylpentyl)carbamate Hydrochloride
- Carbamic acid, N-[(1R,4R)-4-amino-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester, hydrochloride (1:1)
- Thiazol-5-ylmethyl (2R,5R)-5-amino-1,6-diphenylhexan-2-ylcarbaMate hydrochloride
Description:
Applications Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride is an impurity of Cobicistat (C633150), a HIV protease inhibitor that has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer.
References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
446.0
Formula:
C23H27N3O2S·HCl
Color/Form:
Neat
InChI:
InChI=1S/C23H27N3O2S.ClH/c24-20(13-18-7-3-1-4-8-18)11-12-21(14-19-9-5-2-6-10-19)26-23(27)28-16-22-15-25-17-29-22;/h1-10,15,17,20-21H,11-14,16,24H2,(H,26,27);1H/t20-,21-;/m1./s1
InChI key:
InChIKey=UPZSMWCRMXVNOX-MUCZFFFMSA-N
SMILES:
Cl.N[C@H](CC[C@H](Cc1ccccc1)NC(=O)OCc1cncs1)Cc1ccccc1
MDL:
Melting point:
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Density:
Concentration:
EINECS:
Merck:
HS code:
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