6-Thioinosine Phosphate

CAS: 53-83-8

Ref. TR-T344500

Product Information

• Name: 6-Thioinosine Phosphate
• Synonyms: [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-sulfanylidene-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate, 5'-Inosinic acid, 6-thio- (9CI), 5′-Inosinic acid, 6-thio-, 6-Mercaptopurine ribo-5′-monophosphate, 6-Mercaptopurine ribonucleoside 5′-phosphate, 6-Mercaptopurine ribonucleoside monophosphate, 6-Mercaptopurine ribonucleotide, 6-Mercaptopurine riboside 5'-monophosphate, 6-Mercaptopurine riboside 5'-phosphate, 6-Mercaptopurine riboside phosphate, 6-Mercaptopurine ribotide, 6-Thio-5′-inosinic acid, 6-Thio-IMP, 6-Thioinosine 5'-phosphate (VAN), 6-Thioinosine 5′-phosphate, 6-Thioinosine 5′-phosphoric acid, 6-Thioinosinic acid, 9-(5-O-phosphono-beta-D-ribofuranosyl)-3,9-dihydro-6H-purine-6-thione, 9-(5-O-phosphonopentofuranosyl)-3,9-dihydro-6H-purine-6-thione, 9H-Purine-6-thiol, 9-beta-D-ribofuranosyl-, 5'-(dihydrogen phosphate) (8CI), 9H-Purine-6-thiol, 9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 5′-(dihydrogen phosphate), 9H-Purine-6-thiol, 9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 5′-phosphate, Nsc 520722, Thio-IMP, Thioinosinic acid, 9H-Purine-6-thiol, 9-β-D-ribofuranosyl-, 5′-(dihydrogen phosphate), 9H-Purine-6-thiol, 9-β-D-ribofuranosyl-, 5′-phosphate

Description

Stability Hygroscopic
Applications A metabolite of 6-Mercaptopurine.
References Parker, W., et al.: Cancer Res., 51, 2386 (1991) , Munagala, N., et al.: J. Biol. Chem., 275, 37072 (2000), Guddat, L., et al.: Protein Sci., 11, 1626 (2002), Pinkel, D., et al.: J. Clin. Oncol., 11, 1826 (1993), Tripathy, D., et al.: Oncologist, 12, 375 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 364.27
• Formula: C₁₀H₁₃N₄O₇PS
• Purity: ~90%
• Color/Form: Neat
• InChI: InChI=1S/C10H13N4O7PS/c15-6-4(1-20-22(17,18)19)21-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)23/h2-4,6-7,10,15-16H,1H2,(H,11,12,23)(H2,17,18,19)/t4-,6-,7-,10-/m1/s1
• InChI key: InChIKey=ZKRFOXLVOKTUTA-KQYNXXCUSA-N
• SMILES: O=P(O)(O)OC[C@H]1O[C@@H](n2cnc3c(=S)nc[nH]c32)[C@H](O)[C@@H]1O