Estimated delivery in United States, on Tuesday 21 May 2024
Product Information
Name:
TIQ-A
Controlled Product
Synonyms:
- Thieno[2,3-C]isoquinolin-5-one
- Thieno(2,3-C)Isoquinolin-5-One
- Tiq-A
CAS:
Description:
Applications A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).
References Chiarugi, A., et al.: J. Pharmacol. Exp. Ther., 305, 43 (2003), pellicciari, R., et al.: Farmaco., 58, 851 (2003)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
201.24
Formula:
C11H7NOS
Color/Form:
Brown to Dark Blue Solid
InChI:
InChI=1S/C11H7NOS/c13-10-8-4-2-1-3-7(8)9-5-6-14-11(9)12-10/h1-6H,(H,12,13)
InChI key:
InChIKey=LQJVOLSLAFIXSV-UHFFFAOYSA-N
SMILES:
O=c1[nH]c2sccc2c2ccccc12
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-T445100 TIQ-A
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