Tofacitinib Impurity Z
CAS: 477600-76-3
Ref. TR-T528030
| 10mg | Discontinued | ||
| 25mg | Discontinued | ||
| 100mg | Discontinued |
Product Information
Name:
Tofacitinib Impurity Z
Synonyms:
- 1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one,1-[(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]ethanone
Description:
Impurity Tofacintinib Impurity
Applications Tofacitinib Impurity Z is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3 (Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
References Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
287.36
Formula:
C15H21N5O
Color/Form:
White Solid
InChI:
InChI=1S/C15H21N5O/c1-10-5-7-20(11(2)21)8-13(10)19(3)15-12-4-6-16-14(12)17-9-18-15/h4,6,9-10,13H,5,7-8H2,1-3H3,(H,16,17,18)/t10-,13+/m1/s1
InChI key:
InChIKey=FJIVGKFVGCGMFC-MFKMUULPSA-N
SMILES:
CC(=O)N1CC[C@@H](C)[C@@H](N(C)c2ncnc3[nH]ccc23)C1
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