N-Tri-boc Tobramycin

CAS: 502610-97-1

Ref. TR-T733810

Product Information

• Name: N-Tri-boc Tobramycin
• Synonyms: O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-[2,3,6-trideoxy-2,6-bis[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-D-ribo-hexopyranosyl-(1-4)]-2-deoxy-N3-[(1,1-dimethylethoxy)carbonyl]-D-streptamine

Description

Applications N-Tri-boc Tobramycin is an intermediate in synthesizing 1-N-Ureido Tobramycin Tetrahydrochloride Salt (U824490), which is the HCl salt form of 1-N-Ureido Tobramycin which is a related compound of Tobramycin (T524000), single factor antibiotic comprising about 10% of nebramycin, the aminoglycosidic antibiotic complex produced by Streptomyces tenebrarius. Antibacterial.
References Koch, K.F., et al.: Antimicrob. Agents Chemother., 309 (1970); Welles, J.S., et al.: Toxicol. Appl. Pharmacol., 22, 332 (1972); Dash, A.K., et al.: Anal. Profiles Drug Subs. Excip., 24, 579 (1996)

• Brand: TRC

Chemical properties

• Molecular weight: 767.86
• Formula: C₃₃H₆₁N₅O₁₅
• Color/Form: White Solid
• InChI: InChI=1S/C33H61N5O15/c1-31(2,3)51-28(44)36-12-18-17(40)11-16(38-30(46)53-33(7,8)9)26(47-18)50-25-15(37-29(45)52-32(4,5)6)10-14(34)24(23(25)43)49-27-22(42)20(35)21(41)19(13-39)48-27/h14-27,39-43H,10-13,34-35H2,1-9H3,(H,36,44)(H,37,45)(H,38,46)/t14-,15+,16-,17+,18-,19-,20+,21-,22-,23-,24+,25-,26-,27-/m1/s1
• InChI key: InChIKey=QQSQYHDYSQMVDL-LOBSLKQUSA-N
• SMILES: CC(C)(C)OC(=O)NC[C@H]1O[C@H](O[C@@H]2[C@@H](NC(=O)OC(C)(C)C)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](NC(=O)OC(C)(C)C)C[C@@H]1O