2'-Triethylsilyldocetaxel

CAS: 162871-12-7

Ref. TR-T778020

Product Information

• Name: 2'-Triethylsilyldocetaxel
• Synonyms: (alphaR,betaS)-beta-[[(1,1-Dimethylethoxy)carbonyl]amino]-alpha-[(triethylsilyl)oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester
• CAS: 162871-12-7

Description

Applications Used in the preparation of ester-linked docetaxel-monosaccharide conjugates.
References Shimoda, K. & Kubota, N.: Molecules, 16, 6769 (2011)

• Brand: TRC

Chemical properties

• Molecular weight: 922.14
• Formula: C₄₉H₆₇NO₁₄Si
• Color/Form: White Solid
• InChI: InChI=1S/C49H67NO14Si/c1-12-65(13-2,14-3)64-38(36(30-21-17-15-18-22-30)50-44(57)63-45(6,7)8)43(56)60-32-26-49(58)41(61-42(55)31-23-19-16-20-24-31)39-47(11,40(54)37(53)35(28(32)4)46(49,9)10)33(52)25-34-48(39,27-59-34)62-29(5)51/h15-24,32-34,36-39,41,52-53,58H,12-14,25-27H2,1-11H3,(H,50,57)/t32-,33-,34+,36-,37+,38+,39-,41-,47+,48-,49+/m0/s1
• InChI key: InChIKey=SNFQGZFZXWNAEJ-MUQZGBOESA-N
• SMILES: CC[Si](CC)(CC)O[C@@H](C(=O)O[C@H]1C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)[C@H]3[C@](C)(C(=O)[C@H](O)C(=C1C)C2(C)C)[C@@H](O)C[C@H]1OC[C@]13OC(C)=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1