Estimated delivery in United States, on Tuesday 21 May 2024
Product Information
Name:
TRV-130 Hydrochloric Acid Salt
Synonyms:
- Oliceridine
- (9R)-N-[(3-methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine
- monohydrochloride
- (9R)-N-[(3-Methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine hydrochloride (1:1)
- 6-Oxaspiro[4.5]decane-9-ethanamine, N-[(3-methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-, hydrochloride (1:1), (9R)-
CAS:
Description:
Applications TRV-130 is a μ-opioid receptor (MOR) G protein-biased ligand. It is potently analgesic while causing less gastrointestinal dysfunction and respiratory suppression than morphine at equianalgesic doses.
References DeWire, S., et al.: J. Pharm. Exper. Ther., 344, 708 (2013); Soergel, D., et al.: Pain, 155, 1829 (2014)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
423.01
Formula:
C22H31ClN2O2S
Color/Form:
Neat
InChI:
InChI=1S/C22H30N2O2S.ClH/c1-25-18-7-15-27-19(18)16-23-13-10-21(20-6-2-5-12-24-20)11-14-26-22(17-21)8-3-4-9-22;/h2,5-7,12,15,23H,3-4,8-11,13-14,16-17H2,1H3;1H/t21-;/m1./s1
InChI key:
InChIKey=YIIWXYLJZRISQP-ZMBIFBSDSA-N
SMILES:
COc1ccsc1CNCC[C@@]1(c2ccccn2)CCOC2(CCCC2)C1.Cl
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-T895530 TRV-130 Hydrochloric Acid Salt
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