Tylvalosin-d9

CAS: 63409-12-1

Ref. TR-T898212

Product Information

• Name: Tylvalosin-d9
• Synonyms: [(2S,3S,4R,6S)-6-[(2R,3R,4S,5S,6R)-2-[[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-4-acetoxy-16-ethyl-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-6-methyl-tetrahydropyran-3-yl]oxy-4-hydroxy-2,4-dimethyl-tetrahydropyran-3-yl] 2,2,3,4,4,4-hexadeuterio-3-(trideuteriomethyl)butanoate, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-15-(((6-Deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxy)methyl)-6-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-4-O-(3-methylbutanoyl)-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyl)oxy)-16-ethyl-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl acetate, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-15-{[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl}-6-({3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methylbutanoyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl}oxy)-16-ethyl-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl acetate, 3-Acetyl-4''-isovaleryltylosin, 3-O-Acetyl-4′′-O-isovaleryltylosin, Acetylisovaleryltylosin, Oxacyclohexadecane, tylosin deriv., Tylosin, 3-acetate 4^B-(3-methylbutanoate), Tylvalosin, Tylvalosin [USAN]
• CAS: 63409-12-1

Description

Applications Tylvalosin-d9 is the labeled analogue of Tylvalosin (T898210), an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria.
References Okamoto, R. et al.: J. Antibio., 32, 542 (1979)

• Brand: TRC

Chemical properties

• Molecular weight: 1051.31
• Formula: C₅₃D₉H₇₈NO₁₉
• Purity: >90%
• Color/Form: Light Yellow Solid
• InChI: InChI=1S/C53H87NO19/c1-16-38-36(26-65-51-49(64-15)48(63-14)45(61)32(8)67-51)22-28(4)17-18-37(57)29(5)23-35(19-20-55)46(30(6)39(69-34(10)56)24-41(59)70-38)73-52-47(43(54(12)13)44(60)31(7)68-52)72-42-25-53(11,62)50(33(9)66-42)71-40(58)21-27(2)3/h17-18,20,22,27,29-33,35-36,38-39,42-52,60-62H,16,19,21,23-26H2,1-15H3/b18-17+,28-22+/t29-,30+,31-,32-,33+,35+,36-,38-,39-,42+,43+,44-,45-,46-,47-,48-,49-,50+,51-,52+,53-/m1/s1/i2D3,3D3,21D2,27D
• InChI key: InChIKey=KCJJINQANFZSAM-GYLINRLFSA-N
• SMILES: [2H]C([2H])([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])C(=O)O[C@H]1[C@H](C)O[C@@H](O[C@@H]2[C@@H](C)O[C@@H](O[C@@H]3[C@@H](C)[C@H](OC(C)=O)CC(=O)O[C@H](CC)[C@@H](CO[C@@H]4O[C@H](C)[C@H](O)[C@H](OC)[C@@H]4OC)/C=C(C)/C=C/C(=O)[C@H](C)C[C@@H]3CC=O)[C@H](O)[C@H]2N(C)C)C[C@@]1(C)O