Veralipride

CAS: 66644-81-3

Ref. TR-V122500

Product Information

• Name: Veralipride
• Synonyms: 5-(Aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]benzamide, Agreal, LIR 1660, 2,3-dimethoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-5-sulfamoylbenzamide, 266-435-5, Benzamide, 5-(aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-, Lir 1660, N-(1-Allyl-2-pyrrolidinyl)methyl-2,3-dimethoxy-5-sulfamoylbenzamide, N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-veratramide, N-[(1-Allylpyrrolidin-2-yl)methyl]-2,3-dimethoxy-5-sulfamoylbenzamide, N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(aminosulfonyl)-2,3-dimethoxybenzamide, benzamide, 5-(aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]-
• CAS: 66644-81-3

Description

Applications Veralipride, a synthetic benzamide derivative with antidopaminergic action, is effective in reducing the frequency and severity of hot flashes associated with menopausal hypoestrogenism, gaining interest as a non-hormonal treatment for climacteric flushing.
References Casper, R., et al.: Clin. Endocrinol., 22, 293 (1985), Melis, G., et al.: J. Clin. Endocrinol. Metab., 66, 964 (1988), Stearns, V., et al.: Lancet, 360, 1851 (2002),

• Brand: TRC

Chemical properties

• Molecular weight: 383.46
• Formula: C₁₇H₂₅N₃O₅S
• Color/Form: Neat
• InChI: InChI=1S/C17H25N3O5S/c1-4-7-20-8-5-6-12(20)11-19-17(21)14-9-13(26(18,22)23)10-15(24-2)16(14)25-3/h4,9-10,12H,1,5-8,11H2,2-3H3,(H,19,21)(H2,18,22,23)
• InChI key: InChIKey=RYJXBGGBZJGVQF-UHFFFAOYSA-N
• SMILES: C=CCN1CCCC1CNC(=O)c1cc(S(N)(=O)=O)cc(OC)c1OC