Vicriviroc Maleate

CAS: 599179-03-0

Ref. TR-V250000

Product Information

• Name: Vicriviroc Maleate
• Synonyms: 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-piperidine (2Z)-2-butenedioate (1:1), (4,6-Dimethylpyrimidin-5-yl){4-[(3S)-4-{(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl}-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}methanone (2Z)-but-2-enedioate (1:1), methanone, (4,6-dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]-, (2Z)-2-butenedioate (1:1), Vicriviroc maleate, 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate

Description

Applications Vicriviroc Maleate, is a potent antagonist of CCR5, a G-protein coupled receptor.
References Alonzo III, F., et al.: Nature, 493, 51 (2013); Velasco-Velázquez, M., et al.: Cancer Res., 72, 3839 (2012); Kamp, C., et al.: Virol. J., 7, 55 (2010); Symons, J., et al.: J. Antimicrob. Chemother., 66, 890 (2011)

• Brand: TRC

Chemical properties

• Molecular weight: 649.70
• Formula: C₂₈H₃₈F₃N₅O₂·C₄H₄O₄
• Color/Form: Off White Powder
• InChI: InChI=1S/C28H38F3N5O2.C4H4O4/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8-23(9-7-22)28(29,30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3;5-3(6)1-2-4(7)8/h6-9,18-19,24H,10-17H2,1-5H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t19-,24-;/m0./s1
• InChI key: InChIKey=RPFAXJQGBOULPA-CQLUAUNVSA-N
• SMILES: O=C(O)CCC[C@H](O)/C=C/C=C\CCCCCCCCCO