Product Information
Name:
WZ4002 Hydrobromide
Synonyms:
- N-[3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide Hydrobromide
- Wz4002
- Wz-4002
Description:
Applications WZ4002 is used in biological studies for the preparation of pteridin-7(8H)one-based irreversible inhibitors targeting the epidermal growth factor receptor (EGFR) kinase T790M/L858R mutant.
References Zhou, W., et al.: J. Med. Chem., 56, 7921 (2013)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
494.97 (free amine)
Formula:
C25H27ClN6O3xHBr
Color/Form:
Light Orange Solid
InChI:
InChI=1S/C28H40O14/c1-11(2)6-16(30)39-14-8-27(9-37-13(4)29)15(7-12(14)3)40-23-20(34)22(26(27,5)28(23)10-38-28)42-25-19(33)17(31)18(32)21(41-25)24(35)36/h7,11,14-15,17-23,25,31-34H,6,8-10H2,1-5H3,(H,35,36)/t14-,15+,17?,18+,19?,20+,21?,22+,23+,25-,26+,27+,28-/m0/s1
InChI key:
InChIKey=VADOMOZSAYAVLW-JOEFAFGDSA-N
SMILES:
CC(=O)OC[C@]12C[C@H](OC(=O)CC(C)C)C(C)=C[C@H]1O[C@@H]1[C@H](O)[C@@H](O[C@@H]3OC(C(=O)O)[C@H](O)C(O)C3O)[C@@]2(C)[C@]12CO2
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