Yunnaconitine

CAS: 70578-24-4

Ref. TR-Y100900

Product Information

• Name: Yunnaconitine
• Synonyms: (1α,3α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-8-acetate 14-(4-methoxybenzoate)aconitane-3,8,13,14-tetrol, Isoaconitine (6CI), Vilmorrianine B (7CI), 11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, Aconitane-3,8,13,14-tetrol Deriv., 3α,13-Dihydroxyforesaconitine, Guayewuanine B, Yunaconitine, (1alpha,3alpha,6alpha,14alpha,16beta)-8-Acetoxy-20-ethyl-3,13-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl 4-methoxybenzoate, 11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-3,8,13,14-tetrol deriv., 8-(Acetyloxy)-20-Ethyl-3,13-Dihydroxy-1,6,16-Trimethoxy-4-(Methoxymethyl)Aconitan-14-Yl 4-Methoxybenzoate, Aconitane-3,8,13,14-tetrol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-(4-methoxybenzoate), (1α,3α,6α,14α,16β)-, Isoaconitine, Vilmorrianine B
• CAS: 70578-24-4

Description

Applications Yunnaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformational changes. Yunnaconitine is a deiterpene alkaloid, known to exhibit cytotoxic activity in human leukemic cell.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References He, Y.Q., et al.: J. Pharma. Analysis., 1, 57 (2011); Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010); Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010);

• Brand: TRC

Chemical properties

• Molecular weight: 659.76
• Formula: C₃₅H₄₉NO₁₁
• Color/Form: Neat
• InChI: InChI=1S/C35H49NO11/c1-8-36-16-32(17-41-3)22(38)13-23(43-5)35-21-14-33(40)24(44-6)15-34(47-18(2)37,26(29(35)36)27(45-7)28(32)35)25(21)30(33)46-31(39)19-9-11-20(42-4)12-10-19/h9-12,21-30,38,40H,8,13-17H2,1-7H3/t21-,22-,23+,24+,25-,26+,27+,28-,29-,30-,32+,33+,34-,35+/m1/s1
• InChI key: InChIKey=LLEMSCWAKNQHHA-LRAHXVPISA-N
• SMILES: CCN1C[C@@]2(COC)[C@H]3[C@@H](OC)C4C1C3([C@@H](OC)C[C@H]2O)[C@@H]1C[C@]2(O)[C@@H](OC)C[C@@]4(OC(C)=O)[C@H]1[C@H]2OC(=O)c1ccc(OC)cc1