Estimated delivery in United States, on Tuesday 2 Jul 2024
Product Information
Name:
Zoliflodacin
Synonyms:
- (2R,4S,4aS)-11-Fluoro-1,2,4,4a-tetrahydro-2,4-dimethyl-8-[(4S)-4-methyl-2-oxo-3-oxazolidinyl]spiro[isoxazolo[4,5-g][1,4]oxazino[4,3-a]quinoline-5(6H),5'(2'H)-pyrimidine]-2',4',6'(1'H,3'H)-trione
- AZD 0914
- ETX 0914
CAS:
Description:
Applications Zoliflodacin, is a spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor, and has in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus.
References Huband M. D. et al.: Antimicrob Agents Chemother. 2015 Jan;59(1):467-74;
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
487.44
Formula:
C22H22FN5O7
Color/Form:
White To Light Yellow
InChI:
InChI=1S/C22H22FN5O7/c1-8-7-33-21(32)28(8)17-12-4-11-5-22(18(29)24-20(31)25-19(22)30)16-10(3)34-9(2)6-27(16)14(11)13(23)15(12)35-26-17/h4,8-10,16H,5-7H2,1-3H3,(H2,24,25,29,30,31)/t8-,9+,10-,16+/m0/s1
InChI key:
InChIKey=ZSWMIFNWDQEXDT-ZESJGQACSA-N
SMILES:
C[C@@H]1O[C@H](C)CN2c3c(cc4c(N5C(=O)OC[C@@H]5C)noc4c3F)CC3(C(=O)NC(=O)NC3=O)[C@@H]12
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-Z650055 Zoliflodacin
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