CAS 10183-38-7

Fórmula: C13H23N3O4

InChI: InChI=1S/C13H23N3O4/c1-8(2)6-9(14)12(18)15-7-11(17)16-5-3-4-10(16)13(19)20/h8-10H,3-7,14H2,1-2H3,(H,15,18)(H,19,20)/t9-,10-/m0/s1

Chave InChI: YFBBUHJJUXXZOF-UWVGGRQHSA-N

SMILES: CC(C)C[C@@H](C(=O)NCC(=O)N1CCC[C@H]1C(=O)O)N

H-Leu-Gly-Pro-OH tifluoroacetic acid

CAS: 10183-38-7

H-Leu-Gly-Pro-OH is a tripeptide that is found in the amino acid sequence of angiotensin. It is a potent inhibitor of angiotensin converting enzyme (ACE), which is used to regulate blood pressure and the concentration of electrolytes in the body. H-Leu-Gly-Pro-OH tifluoroacetic acid has been shown to inhibit ACE activity, thereby lowering blood pressure and increasing excretion of sodium ions and potassium ions. Experiments have shown that H-Leu-Gly-Pro-OH tifluoroacetic acid inhibits ACE activity by binding to the N terminal amino group on the enzyme, preventing it from converting angiotensin I into angiotensin II. The C terminal glycine residue on the molecule can be eliminated as an N terminal fragment after hydrolysis with trypsin, or as a C terminal fragment after hydrolysis with papain.

Fórmula: C₁₃H₂₃N₃O₄•(CF₃CO₂H)x

Pureza: Min. 95%

Peso molecular: 285.34 g/mol

Ref: 3D-FL109113

L-Proline, L-leucylglycyl-

CAS: 10183-38-7

Fórmula: C₁₃H₂₃N₃O₄

Peso molecular: 285.3394

Ref: IN-DA0005NV