CAS 102691-36-1

N,N,N',N'-tetraisopropil-fosforodiamidito de 2-cianoetilo

Descrição:

O 2-Cianoetila N,N,N',N'-tetraisopropilfosfordiamidite é um composto químico comumente utilizado no campo da química orgânica, particularmente na síntese de oligonucleotídeos. É caracterizado por sua estrutura de fosforamidite, que apresenta um átomo de fósforo ligado a dois grupos isopropila e um grupo cianoetila, juntamente com dois átomos de nitrogênio dos grupos funcionais amidite. Este composto é tipicamente um líquido incolor a amarelo pálido e é conhecido por sua estabilidade em condições anidras, tornando-o adequado para uso na síntese de ácidos nucleicos. Sua reatividade é atribuída principalmente à parte de fosforamidite, que pode ser ativada para reações de acilo com nucleosídeos. A presença do grupo cianoetila aumenta a solubilidade e reatividade do composto, facilitando seu papel como bloco de construção na formação de ligações fosfodiéster. Precauções de segurança devem ser observadas ao manusear este composto, pois pode representar riscos à saúde se inalado ou ingerido.

Fórmula: C₁₅H₃₂N₃OP

InChI: InChI=1/C15H32N3P/c1-12(2)17(13(3)4)19(11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3

Chave InChI: InChIKey=RKVHNYJPIXOHRW-UHFFFAOYSA-N

SMILES: P(N(C(C)C)C(C)C)(N(C(C)C)C(C)C)OCCC#N

Sinónimos:

• (2-Cyanoethoxy)bis(diisopropylamino)phosphine
• 2-Cyanoethoxybis(N,N-diisopropylamino)phosphine
• 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite
• 2-Cyanoethyl N,N,N,N-tetraisopropyl phosphoramidite
• 2-Cyanoethyl N,N,N,N-tetraisopropylphosphorodiamitide
• 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite
• 2-Cyanoethyl tetraisopropylphosphorodiamidite
• 2-Cyanoethyl-N,N,N¹,N¹-tetraisopropylphosphorodiamidite
• 2-Cyanoethyltetraisopropylphosphorodiamidite
• 2-cyanoethyl N,N,N',N'-tetrapropan-2-ylphosphorodiamidoite
• 3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile
• 3-([Bis[bis(propan-2-yl)amino]phosphanyl]oxy)propanenitrile
• 3-Bis(diisopropylamino)phosphanyloxypropanenitrile
• 3-Bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile
• 3-[Bis(diisopropylamino) phosphinooxy]propanenitrile
• Bis(diisopropylamino)(2-cyanoethoxy)phosphine
• Bis(diisopropylamino)-2-cyanoethoxyphosphane
• P-(2-cyanoethyl)-N,N,N',N'-tetrapropan-2-ylphosphonous diamide
• Phosphorodiamidous acid, N,N,N′,N′-tetrakis(1-methylethyl)-, 2-cyanoethyl ester
• Phosphorodiamidous acid, tetrakis(1-methylethyl)-, 2-cyanoethyl ester
• β-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite
• β-Cyanoethyl-N,N,N′,N′-tetraisopropyldiamidophosphite
• 2-CYANOETHYL-N,N,N'',N''-TETRAISO-PROPYLPHOSPHORAMIDITE(P-REAGENT)
• 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite 98%
• TETRAISOPROPYLPHOSPHORODIAMIDITE
• 5) 2-cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite
• β-Cyanoethyl-N,N,N`,N`-tertraisopropylphosphorodia
• P-REAGENT
• Bis(diisopropylamino)(2-cyanoethoxy)phosphine P-Reagent

2-Cyanoethyl N,N,N',N'-Tetraisopropylphosphordiamidite

CAS: 102691-36-1

Fórmula: C₁₅H₃₂N₃OP

Pureza: >95.0%(GC)(T)

Cor e Forma: Colorless to Light orange to Yellow clear liquid

Peso molecular: 301.41

Ref: 3B-C2228

2-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%

Fórmula: (CH₃)₂CHNPOCH₂CH₂CN

Pureza: min. 98%

Cor e Forma: colorless liq.

Peso molecular: 301.41

Ref: 08-15-0695

2-Cyanoethyl-N,N,N'',N''-tetraisopropylphosphordiamidite (P-Reagent)

CAS: 102691-36-1

Fórmula: C₁₅H₃₂N₃OP

Pureza: (GC) ≥ 94.0%

Cor e Forma: Colourless to light yellow liquid

Peso molecular: 301.41

Ref: 7W-GE1115

2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite

Fórmula: C₁₅H₃₂N₃OP

Pureza: 93%

Cor e Forma: Colourless to pale yellow. Liquid-Viscous

Peso molecular: 301.40784

Ref: 54-OR5367

Bis(diisopropylamino)(2-cyanoethoxy)phosphine

CAS: 102691-36-1

Fórmula: C₁₅H₃₂N₃OP

Pureza: 98%

Cor e Forma: Liquid

Peso molecular: 301.4078

Ref: IN-DA00084L

2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite

Produto Controlado

CAS: 102691-36-1

Stability Explodes When Heated
Applications 2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite (cas# 102691-36-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Fórmula: C₁₅H₃₂N₃OP

Cor e Forma: Neat

Peso molecular: 301.41

Ref: TR-C982100

3-((Bis(diisopropylamino)phosphino)oxy)-propanenitrile

CAS: 102691-36-1

Fórmula: C₁₅H₃₂N₃OP

Pureza: 90.0%

Cor e Forma: Liquid

Peso molecular: 301.415

Ref: 10-F213122

2-Cyanoethyl tetraisopropylphosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl tetraisopropylphosphorodiamidite is widely used for the preparation of modified and unmodified nucleoside phosphoramidites. Nucleoside phosphoramidites are attractive reagents for polymer-supported synthesis of oligonucleotides. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on a protected nucleoside.

Fórmula: C₁₅H₃₂N₃OP

Pureza: (%) Min. 95.0%

Cor e Forma: Colorless Slightly Yellow Clear Liquid

Peso molecular: 301.42 g/mol

Ref: 3D-FC03165

2-Cyanoethyl N,N,N′,N′-Tetraisopropylphosphoramidite

CAS: 102691-36-1

3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile

Fórmula: C₁₅H₃₂N₃OP

Pureza: 97%

Peso molecular: 301.41

Ref: IN-DG40171

1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11

Produto Controlado

CAS: 102691-36-1

Applications 1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11 is an intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine.
References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)

Fórmula: C₁₅D₁₁H₈NO₂

Cor e Forma: Neat

Peso molecular: 256.385

Ref: TR-C982102