CAS 1030759-58-0

Fórmula: C18H20N4O4S

InChI: InChI=1S/C18H20N4O4S/c1-14-4-6-15(7-5-14)27(23,24)22-10-8-21(9-11-22)13-17-19-18(20-26-17)16-3-2-12-25-16/h2-7,12H,8-11,13H2,1H3

Chave InChI: BIMKUWYNAWNDAH-UHFFFAOYSA-N

SMILES: CC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)CC3=NC(=NO3)C4=CC=CO4

FO-4-15

CAS: 1030759-58-0

FO-4-15 is an activator of mGluR1/CaMKIIα. It exhibits protective effects against H2O2 in human neuroblastoma (SH-SY5Y) cells. In mice with Alzheimer's disease, FO-4-15 enhances cognitive function by activating the mGluR1/CaMKIIα pathway, reducing Aβ accumulation, Tau hyperphosphorylation, and synaptic damage.

Fórmula: C₁₈H₂₀N₄O₄S

Cor e Forma: Solid

Peso molecular: 388.44

Ref: TM-T200203