CAS 103146-26-5

Benzenonitrilo, 4-[4-(dimetilamino)-1-(4-fluorofenil)-1-hidroxibutil]-3-(hidroximetil)-, hidrobrometo (1:1)

Descrição:

Benzenonitrilo, 4-[4-(dimetilamino)-1-(4-fluorofenil)-1-hidroxibutil]-3-(hidroximetil)-, hidrobrometo (1:1), com número CAS 103146-26-5, é um composto químico caracterizado por sua estrutura complexa, que inclui um grupo benzonitrilo e vários grupos funcionais, como dimetilamino, hidroxilo e grupos fluorofenila. Este composto normalmente exibe propriedades associadas tanto a nitrilos orgânicos quanto a aminas, incluindo potencial solubilidade em solventes polares devido à presença de grupos hidroxilo e amino. Pode demonstrar atividade biológica, tornando-se de interesse na pesquisa farmacêutica, particularmente no desenvolvimento de medicamentos que visam receptores ou vias específicas. A forma de sal de hidrobrometo indica que é provável que seja mais estável e solúvel em soluções aquosas em comparação com sua forma de base livre. Assim como muitos compostos orgânicos, sua reatividade pode ser influenciada pela presença do átomo de flúor, que pode afetar as propriedades eletrônicas e interações com sistemas biológicos. Dados de segurança e precauções de manuseio devem ser observados devido à sua potencial toxicidade e reatividade.

Fórmula: C₂₀H₂₃FN₂O₂·BrH

InChI: InChI=1S/C20H23FN2O2.BrH/c1-23(2)11-3-10-20(25,17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24;/h4-9,12,24-25H,3,10-11,14H2,1-2H3;1H

Chave InChI: InChIKey=RVGFHORHCHHPCZ-UHFFFAOYSA-N

SMILES: C(CCCN(C)C)(O)(C1=C(CO)C=C(C#N)C=C1)C2=CC=C(F)C=C2.Br

Sinónimos:

• 4-[(4-Dimethylamino)-1-(4-Fluoro Phenyl)-1-Hydroxybutyl]-3-Hydroxy-Methyl Benzonitrile Hydrobromide
• 4-[4-(Dimethylamino)-1-(4'-Fluorophenyl)-1-(Hydroxybutyl-3-(Hydroxymethyl)) Benzonitrile .Hydrobromic
• 4-[4-(Dimethylamino)-1-(4-Fluorophenyl)-1-HydroxyButyl]-3-(Hydroxymethyl)-Benzon
• 4-[4-(Dimethylamino)-1-(4-Fluorophenyl)-1-Hydroxybutyl]-3-(Hydroxymethyl)-Benzonitrile, Monohydrobromide
• Benzonitrile, 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-, hydrobromide (1:1)
• Benzonitrile, 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-, monohydrobromide
• 4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile hydrobromide

4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hydrobromide

CAS: 103146-26-5

Fórmula: C₂₀H₂₄BrFN₂O₂

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 423.3192

Ref: IN-DA003908

4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hydrobromide

CAS: 103146-26-5

4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hydrobromide

Fórmula: C₂₀H₂₄BrFN₂O₂

Pureza: >98%

Peso molecular: 423.32

Ref: 54-PC100029

Citadiol HBr

CAS: 103146-26-5

Fórmula: C₂₀H₂₃FN₂O₂·HBr

Cor e Forma: White To Off-White Solid

Peso molecular: 342.42 80.91

Ref: 4Z-C-0932

Citadiol Hydrobromide (4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile Hydrobromide)

CAS: 103146-26-5

Cor e Forma: White

Ref: 86-MM0242.26

Citalopram Dihydroxy Impurity

CAS: 103146-26-5

Fórmula: C₂₀H₂₃FN₂O₂HBr

Peso molecular: 342.4 : 80.9

Ref: ST-EA-CP-C23008

4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hydrobromide

CAS: 103146-26-5

Pureza: 98%

Peso molecular: 423.3259888

Ref: 10-F622098

Citadiol Hydrobromide

Produto Controlado

CAS: 103146-26-5

Impurity Citalopram Dihydroxy Impurity
Stability Hygroscopic
Applications Citadiol Hydrobromide is a precursor of Citalopram (C505000), an antidepressant.
References Gerykk, R., et. al.: Chromatographia, 76, 483 (2013); Rao, R.N., Raju, A.N.: J. Pharmaceut. Biomed., 43, 311 (2007)

Fórmula: C₂₀H₂₃FN₂O₂·BrH

Cor e Forma: Neat

Peso molecular: 423.32

Ref: TR-C504800

4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile hydrobromide

CAS: 103146-26-5

4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile hydrobromide is an antagonist of the nicotinic acetylcholine receptor (nAChR) that has been shown to be prophylactic against mediated nitrogen. It was isolated from a marine sponge and shows high affinity for nAChRs, with low nanomolar binding constants. The prophylactic properties of 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile hydrobromide are mediated by its ability to antagonize the function of nAChRs and prevent the release of neurotransmitters such as acetylcholine.

Fórmula: C₂₀H₂₃FN₂O₂•HBr

Pureza: Min. 95%

Peso molecular: 423.32 g/mol

Ref: 3D-FD102304