CAS: 1032900-25-6 - Ceritinib

Fórmula: C₂₈H₃₆ClN₅O₃S

InChI: InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)

Chave InChI: InChIKey=VERWOWGGCGHDQE-UHFFFAOYSA-N

SMILES: O=S(=O)(C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC=3C=C(C(=CC3OC(C)C)C4CCNCC4)C)C(C)C

Sinónimos:

• 2,4-Pyrimidinediamine, 5-chloro-N⁴-[2-[(1-methylethyl)sulfonyl]phenyl]-N²-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-
• 5-Chloro-N4-(2-((1-Methylethyl)Sulfonyl)Phenyl)-N2-(5-Methyl-2-(1-Methylethoxy)-4-(4-Piperidinyl)Phenyl)-2,4-Pyrimidinediamine
• 5-Chloro-N⁴-[2-[(1-methylethyl)sulfonyl]phenyl]-N²-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine
• Ldk 378
• Ldk378
• Zykadia

Ceritinib

CAS: 1032900-25-6

• Fórmula: C₂₈H₃₆ClN₅O₃S
• Cor e Forma: White To Off-White Solid
• Peso molecular: 558.14

LDK378

CAS: 1032900-25-6

Ceritinib

CAS: 1032900-25-6

Ceritinib (LDK378) is a specific ALK inhibitor (IC50: 0.2 nM).

• Fórmula: C₂₈H₃₆ClN₅O₃S
• Pureza: 100%
• Cor e Forma: Solid
• Peso molecular: 558.14

Ceritinib

CAS: 1032900-25-6

ALK receptor tyrosine kinase inhibitor

• Fórmula: C₂₈H₃₆ClN₅O₃S
• Pureza: Min. 95%
• Cor e Forma: Powder
• Peso molecular: 558.14 g/mol

5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine

CAS: 1032900-25-6

Applications 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, is a Anaplastic lymphoma kinase (ALK) inhibitor. References Marsilje, T. H., et al.: …

• Fórmula: C₂₈H₃₆ClN₅O₃S
• Cor e Forma: Neat
• Peso molecular: 558.14

5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine

CAS: 1032900-25-6

• Fórmula: C₂₈H₃₆ClN₅O₃S
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 558.1351