CAS 1046787-18-1

Fórmula: C25H37FN8O2

InChI: InChI=1S/C25H37FN8O2/c1-15-12-33(16(2)11-32(15)13-18-6-8-36-9-7-18)24(35)34-14-19-21(25(34,4)5)30-31-22(19)29-23-20(26)10-27-17(3)28-23/h10,15-16,18H,6-9,11-14H2,1-5H3,(H2,27,28,29,30,31)/t15-,16+/m1/s1

Chave InChI: DKXZBPBWIGORKP-CVEARBPZSA-N

SMILES: C[C@H]1CN([C@@H](CN1C(=O)N2CC3=C(C2(C)C)NN=C3NC4=NC(=NC=C4F)C)C)CC5CCOCC5

5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-ylmethyl)piperazin-1-yl]carbonyl}-N-(5-fluoro-2-methylpyrimidin-4-yl)-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine

CAS: 1046787-18-1

Fórmula: C₂₅H₃₇FN₈O₂

Pureza: 98.79%

Peso molecular: 500.6121

Ref: IN-DA008TMX

PKC-IN-1

CAS: 1046787-18-1

PKC-IN-1 is a highly specific protein kinase C (PKC) inhibitor, which is synthetically derived to target PKC isoforms selectively. Its mode of action involves the inhibition of PKC activity through competitive binding at the ATP-binding site, effectively modulating the phosphorylation of downstream substrates. This regulatory effect on PKC activity makes it an essential tool for elucidating the role of PKC in various signaling pathways.

Fórmula: C₂₅H₃₇FN₈O₂

Pureza: Min. 95%

Peso molecular: 500.61 g/mol

Ref: 3D-WRB78718

PKC-IN-1

CAS: 1046787-18-1

PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,

Fórmula: C₂₅H₃₇FN₈O₂

Pureza: 98% - 98.79%

Cor e Forma: White Solid

Peso molecular: 500.6121

Ref: TM-T12494