CAS 1055986-67-8

Fórmula: C23H22ClN5O3S

InChI: InChI=1S/C23H21N5O3S.ClH/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21;/h1-6,11,13H,7-10,12,14H2,(H,24,32);1H

Chave InChI: IKQFRXPMBGQJGE-UHFFFAOYSA-N

SMILES: C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6.Cl

Amuvatinib hydrochloride

CAS: 1055986-67-8

Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.

Fórmula: C₂₃H₂₂ClN₅O₃S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 483.97

Ref: TM-T14282

Amuvatinib hydrochloride

CAS: 1055986-67-8

Amuvatinib hydrochloride is a multitargeted receptor tyrosine kinase inhibitor that binds to the stem cell factor receptor (SCFR) and other receptors, including the RET, AXL, KIT, PDGFRβ, and FLT3. Amuvatinib hydrochloride can be used to treat cancer by inhibiting SCFR activity. It also inhibits the activity of oncoproteins such as c-KIT, RET, and PDGFRβ. This drug has been shown to inhibit the proliferation of cancer cells in vitro and in vivo models. Amuvatinib hydrochloride has been shown to inhibit DNA repair by preventing DNA damage from being repaired. It also prevents cell division by inhibiting protein synthesis at a step downstream of protein translation.

Fórmula: C₂₃H₂₂ClN₅O₃S

Pureza: Min. 95%

Peso molecular: 484 g/mol

Ref: 3D-FSB98667