CAS 1093793-05-5

Fórmula: C18H17N7O3

InChI: InChI=1S/C18H17N7O3/c1-10(23-24-18(19)20)11-5-7-13(8-6-11)21-17(26)14-9-12-3-2-4-15(25(27)28)16(12)22-14/h2-9,22H,1H3,(H,21,26)(H4,19,20,24)/b23-10+

Chave InChI: ZKHRFTLMLVMQMS-AUEPDCJTSA-N

SMILES: C/C(=N\N=C(N)N)/C1=CC=C(C=C1)NC(=O)C2=CC3=C(N2)C(=CC=C3)[N+](=O)[O-]

PV-1019

CAS: 1093793-05-5

PV-1019 (NSC 744039), a potent Chk2 inhibitor, has an IC50 of 24 nM and blocks Chk2 autophosphorylation and IR-induced apoptosis.

Fórmula: C₁₈H₁₇N₇O₃

Cor e Forma: Solid

Peso molecular: 379.37

Ref: TM-T73411