CAS 1110873-99-8

Fórmula: C21H19F3N4O4S

InChI: InChI=1S/C21H19F3N4O4S/c1-13-10-15(32-27-13)12-33-19-5-3-2-4-16(19)20(29)26-9-8-25-17-7-6-14(21(22,23)24)11-18(17)28(30)31/h2-7,10-11,25H,8-9,12H2,1H3,(H,26,29)

Chave InChI: BPHPWPNHNGXNPR-UHFFFAOYSA-N

SMILES: CC1=NOC(=C1)CSC2=CC=CC=C2C(=O)NCCNC3=C(C=C(C=C3)C(F)(F)F)[N+](=O)[O-]

RU-301

CAS: 1110873-99-8

RU-301

Fórmula: C₂₁H₁₉F₃N₄O₄S

Pureza: ≥98%

Peso molecular: 480.46

Ref: 54-BUP02810

2-{[(3-methyl-1,2-oxazol-5-yl)methyl]sulfanyl}-N-(2-{[2-nitro-4-(trifluoromethyl)phenyl]amino}ethyl)benzamide

CAS: 1110873-99-8

Fórmula: C₂₁H₁₉F₃N₄O₄S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 480.4602

Ref: IN-DA01C2JV

RU-301

CAS: 1110873-99-8

RU-301 is a novel pan-tam inhibitor

Fórmula: C₂₁H₁₉F₃N₄O₄S

Pureza: 98.87%

Cor e Forma: Solid

Peso molecular: 480.46

Ref: TM-T7425

RU-301

CAS: 1110873-99-8

2-{[(3-methyl-1,2-oxazol-5-yl)methyl]sulfanyl}-N-(2-{[2-nitro-4-(trifluoromethyl)phenyl]amino}ethyl)benzamide

Fórmula: C₂₁H₁₉F₃N₄O₄S

Pureza: 98%

Peso molecular: 480.46

Ref: IN-DG01025561

RU-301

CAS: 1110873-99-8

RU-301 is a potential therapeutic agent for cancer. It is an inhibitor of the tumor suppressor protein p53 and its homologs, which are known to play a role in regulating cell cycle progression and suppressing tumorigenicity. RU-301 has been shown to inhibit the activity of h1299 cells in vitro by inhibiting extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation, leading to decreased tumorigenicity. In addition, RU-301 may have anti-angiogenic properties due to its ability to decrease vascular endothelial growth factor production and angiogenesis. Biochemical assays have also shown that RU-301 inhibits the proliferation of various cancer cell lines such as A549, H1299, and HT29 cells. RU-301 may be a promising candidate for cancer therapy due to its ability to inhibit both tumor suppressors and cellular proliferation.

Fórmula: C₂₁H₁₉F₃N₄O₄S

Pureza: Min. 95%

Peso molecular: 480.46 g/mol

Ref: 3D-KUB87399