CAS 1130067-06-9

Fórmula: C26H28Cl2N4O2

InChI: InChI=1S/C26H27ClN4O2.ClH/c1-17(28-25(32)20-7-6-18-4-2-3-5-19(18)14-20)16-30-12-10-22(11-13-30)31-24-9-8-21(27)15-23(24)29-26(31)33;/h2-9,14-15,17,22H,10-13,16H2,1H3,(H,28,32)(H,29,33);1H/t17-;/m0./s1

Chave InChI: RQULTQQAHGYYDG-LMOVPXPDSA-N

SMILES: C[C@@H](CN1CCC(CC1)N2C3=C(C=C(C=C3)Cl)NC2=O)NC(=O)C4=CC5=CC=CC=C5C=C4.Cl

VU0155069

CAS: 1130067-06-9

VU0155069

Fórmula: C₂₆H₂₇ClN₄O₂

Pureza: 99.5%

Peso molecular: 462.97

Ref: 54-BUP05641

VU-0155069

CAS: 1130067-06-9

VU-0155069

Fórmula: C₂₆H₂₇ClN₄O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 462.97117

Ref: 54-BISN0085

VU0155069

CAS: 1130067-06-9

Fórmula: C₂₆H₂₈Cl₂N₄O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 499.4321

Ref: IN-DA0081MP

(S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)-2-naphthamide

CAS: 1130067-06-9

Fórmula: C₂₆H₂₇ClN₄O₂

Pureza: ≥98%

Peso molecular: 462.98

Ref: 10-F544995

VU-0155069

CAS: 1130067-06-9

VU-0155069 is a small molecule that inhibits fatty acid uptake and metabolism in the kidney. It has been shown to suppress tumor growth in a mouse model of breast cancer by inhibiting fatty acid uptake and metabolism, which reduces the production of proinflammatory molecules. VU-0155069 also inhibits the cation channel CLCN2 in glioma patients, which leads to reduced tumor growth. This drug has shown efficacy in human clinical trials for patients with chronic kidney disease who have not responded to other therapies. VU-0155069 is being investigated as an adjuvant treatment for glioma patients who have already undergone surgery or radiation therapy. VU-0155069 can be used to treat neurodegenerative diseases such as Parkinson's disease by restoring synaptic dysfunction and reducing inflammation.

Fórmula: C₂₆H₂₇ClN₄O₂

Pureza: Min. 95%

Peso molecular: 462.97 g/mol

Ref: 3D-FVB06706

VU0155069

CAS: 1130067-06-9

VU0155069, a selective PLD1 inhibitor (IC50: 46 nM), halts cancer cell migration in transwell assays.

Fórmula: C₂₆H₂₇ClN₄O₂

Pureza: 99.5%

Cor e Forma: White Solid

Peso molecular: 462.97

Ref: TM-T17239