CAS 113507-06-5

Moxidectina

Descrição:

Moxidectina é uma lactona macrocíclica semissintética pertencente à classe de compostos conhecidos como avermectinas, que são derivados da fermentação da bactéria Streptomyces avermitilis. É utilizado principalmente como agente antiparasitário, particularmente na medicina veterinária, para o tratamento de várias infecções parasitárias em animais, incluindo nematódeos e ectoparasitas. Moxidectina exibe um amplo espectro de atividade e é conhecido por sua longa duração de ação, o que permite uma dosagem menos frequente em comparação com outros agentes antiparasitários. O composto atua ligando-se aos canais de cloro ativados por glutamato no sistema nervoso dos parasitas, levando à paralisia e morte do organismo. Moxidectina é tipicamente administrado por via oral ou por injeção, e sua farmacocinética é caracterizada por boa absorção e distribuição nos tecidos. É importante notar que, embora Moxidectina seja eficaz contra muitos parasitas, não é eficaz contra todos, e seu uso deve ser orientado por recomendações veterinárias para garantir segurança e eficácia.

Fórmula: C₃₇H₅₃NO₈

InChI: InChI=1/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31-/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1

Chave InChI: InChIKey=YZBLFMPOMVTDJY-LSGXYNIPSA-N

SMILES: C(=C\C(C)C)(\C)/[C@H]1O[C@@]2(C[C@@]3(C[C@](O2)(C/C=C(\C)/C[C@@H](C)/C=C/C=C\4/[C@@]5(O)[C@](C(=O)O3)(C=C(C)[C@@H](O)[C@]5(OC4)[H])[H])[H])[H])C/C(=N\OC)/[C@@H]1C

Sinónimos:

• (2aE,4E,4'E,5'S,6R,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-4'-(methoxyimino)-5',6,8,19-tetramethyl-6'-[(2E)-4-methylpent-2-en-2-yl]-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-2H,17H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-17-one
• (6R,23E,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)milbemycin B
• 23-Methoxime-LL-F 28249α
• 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
• Cl 301423
• Cydectin
• Equest
• Milbemycin B, 5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino)-, [6R,23E,25S(E)]-
• Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
• Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
• MilbemycinB
• Moxidextin
• ProHeart 6
• Proheart
• Quest
• Quest (parasiticide)
• Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran], milbemycin B deriv.
• Vetdectin Oral Drench
• Moxidectin@100 μg/mL in Acetonitrile
• [6R,23E,25S(E)]-5-O-DeMethyl-28-deoxy-25-(1,3-diMethyl-1-butenyl)-6,28-epoxy-23-(MethoxyiMino)MilbeMycin B
• Moxidectin powder CAS 113507-06-5 fiona
• Moxidectin Solution, 100ppm
• Moxidectin CRS
• Moxidectin
• (1R,4S,4'E,5'S,6R,6'S,8R,10E,13R,14E,16E,20R,21R,24S)-21,24-dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-[(E)-4-methylpent-2-en-2-yl]spiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
• milbemycin B
• Moxidectin, >=98%
• (2R,2a'E,2a1'S,4Z,4'E,5S,6S,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',20'-Dihydroxy-4-(methoxyimino)-5,6',8',19'-tetramethyl-6-((E)-4-methylpent-2-en-2-yl)-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one
• Milbemycin B,
• Moxidectin for system suitability CRS
• Milbemycin B,5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-buten-1-yl)-6,28-epoxy-23-(methoxyimino)-,(6R,23E,25S)-
• Moxidectin,MilbeMycin B,23-MethoxiMe-LL-F 28249α,Equest,ProHeart 6
• Moxidectin Solution in Methanol, 100μg/mL
• Moxdectin
• (6R,23E,25S)-5-O-DeMethyl-28-deoxy-25-[(1E)-1,3-diMethyl-1-buten-1-yl]-6,28-epoxy-23-(MethoxyiMino)
• Moxidectin HOUSE STANDARD

Moxidectin

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Pureza: >98.0%(N)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 639.83

Ref: 3B-M3136

Moxidectin

CAS: 113507-06-5

Moxidectin

Fórmula: C₃₇H₅₃NO₈

Pureza: 94.2%

Cor e Forma: Off-White

Peso molecular: 639.37712

Ref: 47-1109

MOXIDECTIN CRS

CAS: 113507-06-5

MOXIDECTIN CRS

Fórmula: C₃₇H₅₃NO₈

Cor e Forma: Powder

Peso molecular: 639.8186

Ref: 41-Y0000772

MOXIDECTIN FOR SYSTEM SUITABILITY CRS

CAS: 113507-06-5

MOXIDECTIN FOR SYSTEM SUITABILITY CRS

Fórmula: C₃₇H₅₃NO₈

Cor e Forma: Powder

Peso molecular: 639.8186

Ref: 41-Y0000747

Moxidectin

CAS: 113507-06-5

Lactones, nesoi

Fórmula: C₃₇H₅₃NO₈

Cor e Forma: White Powder

Peso molecular: 639.37712

Ref: 45-1448559

Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 639.8186

Ref: IN-DA00HCQ4

Moxidectin

CAS: 113507-06-5

Moxidectin (CL301423) is an anthelmintic for heartworm/intestinal worms in dogs, cats, horses, cattle, and sheep; oral/topical/injectable.

Fórmula: C₃₇H₅₃NO₈

Pureza: 97.38%

Cor e Forma: Appearance White Or Pale Yellow Amorphous Powder

Peso molecular: 639.82

Ref: TM-T1157

Moxidectin-d3

CAS: 113507-06-5

Fórmula: C₃₇H₅₀D₃NO₈

Peso molecular: 642.85

Ref: 4Z-M-591

Moxidectin

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Cor e Forma: White To Off-White Solid

Peso molecular: 639.84

Ref: 4Z-M-592

Moxidectin

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Pureza: ≥ 95.0%

Cor e Forma: White to off-white or yellow powder

Peso molecular: 639.82

Ref: 7W-GW5324

Moxidectin

CAS: 113507-06-5

Moxidectin

Pureza: ≥95%

Peso molecular: 639.82g/mol

Ref: 54-BUP13574

Moxidectin

CAS: 113507-06-5

Moxidectin

Pureza: 98%

Peso molecular: 639.82g/mol

Ref: 54-OR1030356

PharmaVetResiMix 1 Avermectins-v6 10 µg/mL in Methanol

Produto Controlado

CAS: 113507-06-5, 117704-25-3, 123997-26-2, 155569-91-8, 70288-86-7, 71751-41-2

Cor e Forma: Mixture

Ref: 04-A30000031ME

Moxidectin 100 µg/mL in Acetonitrile

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Cor e Forma: Single Solution

Peso molecular: 639.82

Ref: 04-A15335000AL-100

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3, 113507-06-5, 115550-35-1, 117704-25-3, 119478-55-6, 122-11-2, 1220-83-3, 123997-26-2, 127-71-9, 127-79-7, 144-82-1, 144-83-2, 14698-29-4, 148-79-8, 149676-40-4, 155569-91-8, 19562-30-2, 20559-55-1, 2447-57-6, 28657-80-9, 31430-15-6, 31431-39-7, 389-08-2, 42835-25-6, 43210-67-9, 515-64-0, 51940-44-4, 53716-50-0, 54029-12-8, 54965-21-8, 57-67-0, 57-68-1, 58306-30-2, 59-40-5, 63-74-1, 651-06-9, 68-35-9, 68786-66-3, 70288-86-7, 70458-96-7, 71751-41-2, 72-14-0, 723-46-6, 729-99-7, 74011-58-8, 75184-71-3, 79660-72-3, 80-08-0, 80-32-0, 80-35-3, 80983-34-2, 82419-36-1, 85721-33-1, 88254-99-3, 91296-86-5, 91296-87-6, 93106-60-6, 948-71-0, 98079-52-8

Cor e Forma: Mixture

Ref: 04-K30000030

Moxidectin

Produto Controlado

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Cor e Forma: Neat

Peso molecular: 639.82

Ref: 04-CA15335000

LC PestiMix 2 10 µg/mL in Acetonitrile

CAS: 101-42-8, 103361-09-7, 105512-06-9, 111479-05-1, 111988-49-9, 113507-06-5, 114311-32-9, 116714-46-6, 120116-88-3, 122-34-9, 13360-45-7, 134098-61-6, 134605-64-4, 135158-54-2, 139-40-2, 144550-36-7, 145701-23-1, 14816-18-3, 149979-41-9, 156052-68-5, 158062-67-0, 16118-49-3, 161326-34-7, 1634-78-2, 1646-87-3, 165252-70-0, 16655-82-6, 168316-95-8, 1746-81-2, 177406-68-7, 181587-01-9, 18691-97-9, 1912-26-1, 1967-16-4, 1982-47-4, 19937-59-8, 208465-21-8, 2163-69-1, 2164-08-1, 22248-79-9, 23947-60-6, 24151-93-7, 24307-26-4, 24691-76-7, 2631-40-5, 2655-14-3, 27218-04-8, 272451-65-7, 283594-90-1, 29104-30-1, 298-01-1, 298-02-2, 3060-89-7, 30614-22-3, 330-54-1, 33693-04-8, 34622-58-7, 34681-10-2, 34681-23-7, 361377-29-9, 374726-62-2, 3761-42-0, 3766-60-7, 3766-81-2, 37764-25-3, 3878-19-1, 39196-18-4, 4147-51-7, 500008-45-7, 5234-68-4, 53380-22-6, 55814-41-0, 57646-30-7, 58810-48-3, 62610-77-9, 64628-44-0, 64902-72-3, 66063-05-6, 66215-27-8, 66840-71-9, 68157-60-8, 71283-80-2, 71422-67-8, 72490-01-8, 73250-68-7, 74223-64-6, 76578-14-8, 79241-46-6, 79277-27-3, 81405-85-8, 81412-43-3, 82097-50-5, 82558-50-7, 83-79-4, 83055-99-6, 865318-97-4, 93-71-0, 935545-74-7, 94125-34-5, 94593-91-6, 950-10-7, 999-81-5

Cor e Forma: Mixture

Ref: 04-A50000802AL

Moxidectin

CAS: 113507-06-5

Applications Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);

Fórmula: C₃₇H₅₃NO₈

Cor e Forma: White To Off-White

Peso molecular: 639.82

Ref: TR-M744800

Moxidectin-d3

Produto Controlado

CAS: 113507-06-5

Stability Light Sensitive
Applications Moxidectin-d3 is a the labelled form of Moxidectin (M744800). Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005)

Fórmula: C₃₇H₅₀D₃NO₈

Cor e Forma: White Solid

Peso molecular: 642.84

Ref: TR-M744802

Moxidectin EP H

Produto Controlado

CAS: 113507-06-5

Applications Moxidectin EP H is an impurity of Moxidectin which is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);

Fórmula: C₃₇H₅₁NO₇

Cor e Forma: Neat

Peso molecular: 621.8

Ref: TR-M744815

Moxidectin

CAS: 113507-06-5

Moxidectin is a milbemycin derivative that belongs to the class of macrocyclic lactones. It is used in veterinary medicine to treat infections caused by Diptera larvae, such as the sheep blowfly, Lucilia sericata. Moxidectin has been shown to be an effective drug against c. glabrata, which is resistant to ivermectin and other drugs. Moxidectin binds to P-glycoprotein substrate site 1 and prevents drug efflux from cells by competing with other substrates for binding sites on the transporter. This inhibition of drug efflux may be due to its ability to block P-glycoprotein function or act as a direct inhibitor of ATPase activity. The analytical method used in this study was high performance liquid chromatography (HPLC).

Fórmula: C₃₇H₅₃NO₈

Pureza: Min. 92 Area-%

Cor e Forma: White Powder

Peso molecular: 639.82 g/mol

Ref: 3D-FM31082

Moxidectin - Bio-X ™

CAS: 113507-06-5

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₃₇H₅₃NO₈

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 639.82 g/mol

Ref: 3D-BM300102