CAS 114-07-8: Eritromicina

Descrição: Eritromicina é um antibiótico macrolídeo que é usado principalmente para tratar infecções bacterianas. É derivado da bactéria Saccharopolyspora erythraea e é eficaz contra uma variedade de bactérias Gram-positivas e algumas Gram-negativas. A estrutura química de Eritromicina apresenta um grande anel de lactona, que é característico dos macrolídeos, juntamente com vários grupos de açúcar que contribuem para sua solubilidade e atividade biológica. Eritromicina atua inibindo a síntese de proteínas bacterianas, impedindo assim o crescimento e a reprodução das bactérias. É comumente usado no tratamento de infecções do trato respiratório, infecções de pele e certas infecções sexualmente transmissíveis. Eritromicina está disponível em várias formulações, incluindo comprimidos orais, pomadas tópicas e preparações intravenosas. Embora geralmente seja bem tolerado, pode causar efeitos colaterais como distúrbios gastrointestinais e pode interagir com outros medicamentos devido aos seus efeitos sobre as enzimas hepáticas. A resistência a Eritromicina foi observada em algumas cepas bacterianas, o que pode limitar sua eficácia em certas infecções.

Fórmula: C₃₇H₆₇NO₁₃

InChI: InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

Chave InChI: InChIKey=ULGZDMOVFRHVEP-RWJQBGPGSA-N

SMILES: O=C1OC(CC)C(O)(C)C(O)C(C(=O)C(C)CC(O)(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)C(OC3OC(C)C(O)C(OC)(C)C3)C1C)C

Sinónimos:

• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl propanoate (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,7R,9R,11R,13S,14R)-6-{[(3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• 6-{[4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• Abboticin
• Abomacetin
• Ak-Mycin
• Aknin
• Dotycin
• Drmysin
• E-Base
• E-mycin
• E.E.S
• EMU
• Emgel
• Ergel
• Eritocina
• Eritrex
• Eritrocina
• Eritromed
• Eritromicina
• Ermycin
• Erthrogran
• Ery Derm
• Ery-Ped
• Ery-Tab
• EryDerm
• Eryacne
• Eryc
• Erycen
• Erycette
• Erycin
• Erycinum
• Erygel
• Erymax
• Erytab
• Erythro
• Erythrocin
• Erythrogran
• Erythroguent
• Erythromast
• Erythromast 36
• Erythromid
• Erythromycin A
• Erythromycine
• Ilocap
• Ilosone
• Ilotycin
• Inderm
• L-alpha-Egg-phosphatidylcholine
• Nsc 55929
• Oxacyclotetradecane, erythromycin deriv.
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• P.C.E.
• PCE
• Pantomicina
• Pediamycin
• Retcin
• Robimycin
• Statcin
• Staticin
• Stiemycin
• T-Stat
• Theramycin Z
• Torlamicina
• Torlamicna
• Vetwic
• Wintrocin
• Wyamycin-s
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• Erythromycin

Erythromycin

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Pureza: >98.0%(T)
• Cor e Forma: White to Orange to Green powder to crystal
• Peso molecular: 733.94

Erythromycin, Cell Culture Grade

CAS: 114-07-8

Erythromycin, is used as a macrolide antibiotic protein synthesis inhibitor. It is widely used in …

• Fórmula: C₃₇H₆₇NO₁₃
• Cor e Forma: Crystals or powder or crystalline powder, Translucent or white to pale yellow
• Peso molecular: 733.94

Erythromycin

CAS: 114-07-8

• Fórmula: C₃₆H₆₅NO₁₃/ C₃₇H₆₇NO₁₂/ C₃₇H₆₇NO₁₃
• Pureza: 0.8% / 0.2% / 92.3%
• Cor e Forma: White
• Peso molecular: 719.44559 / 717.46633 / 733.46124

Erythromycin for system suitability CRS

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Peso molecular: 733.9268

Erythromycin for microbiological assay CRS

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Peso molecular: 733.9268

Erythromycin RS

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Peso molecular: 733.9268

Third international Standard for Erythromycin

CAS: 114-07-8

Erythromycin A CRS

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Peso molecular: 733.9268

Erythromycin

CAS: 114-07-8

Erythromycin and its derivatives; salts thereof

• Fórmula: C₃₇H₆₇NO₁₃ErythromycinA
• Cor e Forma: White Light Yellow Powder
• Peso molecular: 733.94 Erythromycin A

[3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 733.9267800000002

Erythromycin

CAS: 114-07-8

Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by …

• Fórmula: C₃₇H₆₇NO₁₃
• Pureza: 99.26% - 99.57%
• Cor e Forma: Hydrated Crystals From Water Physical Description Fluffy Colorless Powder Or Fine White Powder (Ntp 1992)
• Peso molecular: 733.93

Erythromycin

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Pureza: Erythromycin A+B+C: 93.0 - 102.0%
• Cor e Forma: White or pale yellow powder
• Peso molecular: 733.93

Erythromycin

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Pureza: Assay: 96.5% (erythromycin (Typical Value in Batch COA)
• Cor e Forma: white powder
• Peso molecular: 733.93g/mol

Erythromycin

CAS: 114-07-8

• Pureza: ≥98%
• Peso molecular: 733.93g/mol

Erythromycin (Roxithromycin EP Impurity A)

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Cor e Forma: White To Off-White Solid
• Peso molecular: 733.94

Pharmaceuticals Mixture 326 200 µg/mL in Methanol

CAS: 103-90-2 114-07-8298-46-4 56296-78-7 58-08-2 723-46-6 738-70-5 93107-08-5

• Cor e Forma: Mixture

Erythromycin (mixture of A,B,C) 100 µg/mL in Acetonitrile

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Cor e Forma: Single Solution
• Peso molecular: 733.93

(-)-Erythromycin, 98%

CAS: 114-07-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Fórmula: C₃₇H₆₇NO₁₃
• Pureza: 98%
• Cor e Forma: White to light yellow, Powder
• Peso molecular: 733.94

Erythromycin (mixture of A,B,C)

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Cor e Forma: Neat
• Peso molecular: 733.93

Erythromycin 1000 µg/mL in Acetonitrile

CAS: 114-07-8

• Fórmula: C₃₇H₆₇NO₁₃
• Cor e Forma: Single Solution
• Peso molecular: 733.93