CAS 1222-05-5

Galaxolide

Descrição:

Galaxolide, com o número CAS 1222-05-5, é um composto de almíscar sintético amplamente utilizado na indústria de fragrâncias. É caracterizado pelo seu odor agradável e almiscado, que se assemelha ao do almíscar natural. Galaxolide é um líquido incolor a amarelo pálido à temperatura ambiente e é conhecido por sua estabilidade e baixa volatilidade, tornando-o adequado para uso em vários produtos de cuidados pessoais, detergentes e itens domésticos. O composto é lipofílico, permitindo que se misture bem com óleos e gorduras, aumentando sua eficácia como fixador de fragrâncias. Galaxolide é geralmente considerado seguro para uso em cosméticos, embora seu impacto ambiental tenha levantado preocupações devido à sua persistência em ambientes aquáticos. É classificado como um almíscar policíclico, que se refere a um grupo de almíscares sintéticos que podem se acumular no meio ambiente. No geral, o perfil de aroma desejável e a estabilidade de Galaxolide contribuem para sua popularidade em formulações de fragrâncias, enquanto pesquisas contínuas continuam a avaliar seus efeitos ecológicos.

Fórmula: C₁₈H₂₆O

InChI: InChI=1S/C18H26O/c1-11-9-19-10-13-7-15-16(8-14(11)13)18(5,6)12(2)17(15,3)4/h7-8,11-12H,9-10H2,1-6H3

Chave InChI: InChIKey=ONKNPOPIGWHAQC-UHFFFAOYSA-N

SMILES: CC1(C)C=2C(=CC3=C(C2)COCC3C)C(C)(C)C1C

Sinónimos:

• 1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8- HEXAMETHYL CYCLOPENTA-γ-2-BENZOPYRAN
• 1,3,4,6,7,8-Hexahidro-4,6,6,7,8,8-Hexametilindeno[5,6-C]Pirano
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-Hexamethylindeno(5,6-C)Pyr
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-Hexamethylindeno[5,6-C]Pyranne
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclo-penta[g]-2-benzo pyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,8,8,8-hexamethylcyclopenta-2-benzopyran
• 1-[2-(Dimethylamino)-1-(4-Methoxyphenyl)Ethyl]Cyclohexanol Hydrochloride (1:1)
• 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene
• Abbalide
• Cimalide 50
• Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
• Galaxolide
• Galaxolide 50
• Galaxolide 50BB
• Galaxolide 50IPM
• Galaxolide Abbalide
• Galaxolide White
• Hhcb
• Pearlide
• Venlafaxine

1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate)

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Cor e Forma: Colorless to Light yellow clear liquid

Peso molecular: 258.41

Ref: 3B-G0415

Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Pureza: 70%

Cor e Forma: Liquid

Peso molecular: 258.3984

Ref: IN-DA0016XN

Galaxolide

CAS: 1222-05-5

Ref: 7W-GK3703

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene

CAS: 1222-05-5

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene

Pureza: 70%

Peso molecular: 258.40g/mol

Ref: 54-OR1011338

Mix 1 of Musk a. Polycy. Musk Comp. 10 µg/mL in Cyclohexane

CAS: 105-95-3, 1222-05-5, 13171-00-1, 15323-35-0, 21145-77-7, 33704-61-9, 68140-48-7, 81-14-1, 81-15-2, 83-66-9

Fórmula: C₁₄H₂₂O

Cor e Forma: Mixture

Peso molecular: 206.32

Ref: 04-LA19020100CY

HHCB

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Cor e Forma: Neat

Peso molecular: 258.40

Ref: 04-C14213000

HHCB 10 µg/mL in Isooctane

Produto Controlado

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Cor e Forma: Single Solution

Peso molecular: 258.40

Ref: 04-A14213000IO-10

Galaxolide

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Peso molecular: 258.41

Ref: 4Z-G-159001

Galaxolide-13C-d2

CAS: 1222-05-5

Fórmula: CC₁₇H₂₄D₂O

Peso molecular: 261.41

Ref: 4Z-G-159002

Galaxolide-d6 (Mixture of Diastereomers) (>80%)

Produto Controlado

CAS: 1222-05-5

Applications Galaxolide-d6 is the isotope labelled analog of Galaxolide (G189000); a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents.
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y. et al.: Flav. Frag. J., 21, 822 (2006)

Fórmula: C₁₈H₂₀D₆O

Pureza: >80%

Cor e Forma: Neat

Peso molecular: 264.43541

Ref: TR-G189002

Galaxolide (Mixture of Diastereomers)

Produto Controlado

CAS: 1222-05-5

Stability Moisture sensitive
Applications Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents. It is increasingly found in the Great Lakes. An assessment by Green-Screen for Safer Chemicals indicates that it is toxic to aquatic life.This compound is a contaminant of emerging concern (CECs).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y., et al.: Flav. Frag. J., 21, 822 (2006); Chem. and Eng. News, May 2 (2016), page 19

Fórmula: C₁₈H₂₆O

Pureza: >80%

Cor e Forma: Colourless

Peso molecular: 258.40

Ref: TR-G189000

Galaxolide (solution 50% in diethyl phthalate)

Produto Controlado

CAS: 1222-05-5

Applications Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y. et al.: Flav. Frag. J., 21, 822 (2006);

Fórmula: C₁₈H₂₆O

Cor e Forma: Single Solution

Peso molecular: 258.40

Ref: TR-G189001

Galaxolide - Mixture of Diastereomers

CAS: 1222-05-5

Galaxolide is a mixture of diastereomers that has been shown to inhibit the growth of bacteria in wastewater treatment systems. It also has high resistance to oxidation and biological attack, which makes it an ideal candidate for use as an antimicrobial agent. Galaxolide exhibits strong inhibitory properties against bacterial membrane potentials and mitochondrial membrane potential, and displays antioxidant activity in vitro. The molecular docking analysis of galaxolide showed that it binds to the active site of triclosan-induced peroxidase. This binding inhibits the enzyme activity of this enzyme, which is responsible for oxidative injury in cells. The chemical structures of galaxolide have been determined using a variety of analytical methods, including dispersive solid-phase extraction with fluorescence detection.

Fórmula: C₁₈H₂₆O

Pureza: Min. 95%

Cor e Forma: Yellow Powder

Peso molecular: 258.4 g/mol

Ref: 3D-FG23642

Galaxolide-13C3 (Mixture of Diastereomers)

Produto Controlado

CAS: 1222-05-5

Fórmula: C₃C₁₅H₂₆O

Cor e Forma: Neat

Peso molecular: 261.38

Ref: TR-G189003

Galaxolide solution, 50% in diethyl phthalate

CAS: 1222-05-5

Galaxolide is a synthetic fragrance ingredient. It is a mixture of two isomers, alpha- and beta-galaxolide. Galaxolide has been shown to have antimicrobial properties and can be used in the treatment of wastewater. The analytical method for galaxolide includes dispersive solid phase extraction with benzalkonium chloride (BAC). The BAC forms an ionic complex with galaxolide that can then be extracted into organic solvent. Galaxolide also has high resistance to microbial degradation and can be used as an antimicrobial agent in cosmetics.

Fórmula: C₁₈H₂₆O

Pureza: Min. 95%

Cor e Forma: Clear Liquid

Peso molecular: 258.4 g/mol

Ref: 3D-FG45940

Galaxolide

CAS: 1222-05-5

Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), oxidative stress, and genotoxicity. It also stimulates the enzymatic activities of EROD and GST (Glutathione S-transferase).

Fórmula: C₁₈H₂₆O

Cor e Forma: Solid

Peso molecular: 258.40

Ref: TM-T201465