CAS 125971-94-0
:1,1-Dimetiletil (4R,6R)-6-(cianometil)-2,2-dimetil-1,3-dioxano-4-acetato
Descrição:
1,1-Dimetiletil (4R,6R)-6-(cianometil)-2,2-dimetil-1,3-dioxano-4-acetato, com o número CAS 125971-94-0, é um composto químico caracterizado por sua estrutura complexa, que inclui um anel de dioxano e vários grupos funcionais, como um grupo cianometila e um moiety de acetato. Este composto provavelmente exibirá propriedades típicas de derivados de dioxano, incluindo potencial solubilidade em solventes orgânicos e estabilidade sob certas condições. A presença do grupo cianometila sugere reatividade potencial, particularmente em reações de adição nucleofílica. A estereoquímica indicada pela configuração (4R,6R) pode influenciar sua atividade biológica e interações com outras moléculas. Assim como muitos compostos orgânicos, suas propriedades físicas, como ponto de ebulição, ponto de fusão e densidade, dependeriam das interações moleculares específicas e da presença de grupos funcionais. Dados de segurança e precauções de manuseio devem ser consultados, uma vez que compostos com funcionalidades de cianeto podem apresentar riscos de toxicidade. No geral, este composto pode ter aplicações em síntese orgânica ou como um intermediário no desenvolvimento farmacêutico.
Fórmula:C14H23NO4
InChI:InChI=1/C14H23NO4/c1-13(2,3)19-12(16)9-11-8-10(6-7-15)17-14(4,5)18-11/h10-11H,6,8-9H2,1-5H3/t10-,11-/m1/s1
Chave InChI:InChIKey=DPNRMEJBKMQHMC-GHMZBOCLSA-N
SMILES:C(C(OC(C)(C)C)=O)[C@@H]1OC(C)(C)O[C@H](CC#N)C1
Sinónimos:- ((4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-[1,3]dioxan-4-yl)acetic acid tert-butyl ester
- (4R,3R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R,6R)-Tert-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate
- (4R,6R)-t-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)
- (4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-dlmethyl-1,3-dioxane-4-acetate
- (6R-Cyanomethyl-2,2-dimethyl-[1,3]dioxan-4R-yl)acetic acid tert-butyl ester
- 1,1-Dimethylethyl (4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
- 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
- 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R-cis)-
- ATS-8(for Atorvastatin)
- Ast-8
- Atorvastatin Calcium Intermediate ATS-8
- AtorvastatinCalcium(ATS-8)
- Ats-8
- Tert-Butyl (4R,3R)-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate
- Tert-Butyl 2-((4R,6R)-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate
- tert-Butyl(3R,5R)-6-cyano-3,5-O-iso-propylidene-3,5-dihydroxyhexanoate
- tert-butyl [(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
- (4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE(ATS-8)
- Intermediateofatorvastatinecalcium(CAS#134523-03-8)
- (4R,6R)-Tert-Butyl-6-Cyanometh
- 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-1,1-dimethylethylester
- Ats-8:(4R,Cis)-1,1-Dimethylethyl-Cyanomethyl-2,2-Dimethyl
- ATS-8:(4R-CIS)-T-ETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,2-DIMETHYL-1,2-DIONMANO 1 ACETATE
- (4R-Cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dio-cxane-4-acetate
- (4R,6R)-t-Butyl-6-AMINOMETHYL-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R,6R)-t-butyl-6-cyanomethyl02,2-dimethyl-1,3-dioxane-4-acetate
- ATS 8 (4R,CIS)-1,1-DIMETHYLETHY-L-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
- TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-1,3-DIOXAN-4-YL]ACETATE
- (4R-cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dloxane-4-acetate
- Ver mais sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
8 produtos.
tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:Fórmula:C14H23NO4Pureza:>98.0%(GC)(N)Cor e Forma:White to Almost white powder to crystalPeso molecular:269.341,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
CAS:Fórmula:C14H23NO4Pureza:95%Cor e Forma:SolidPeso molecular:269.3367Tert-Butyl 2-((4R,6R)-6-(Cyanomethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate
CAS:Tert-Butyl 2-((4R,6R)-6-(Cyanomethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)AcetatePureza:99%Peso molecular:269.34g/molAtorvastatin Impurity 21
CAS:Fórmula:C14H23NO4Cor e Forma:White To Off-White SolidPeso molecular:269.34(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
CAS:Produto ControladoApplications (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),Fórmula:C14H23NO4Cor e Forma:NeatPeso molecular:269.34Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6R)-Isomer
CAS:Fórmula:C14H23NO4Peso molecular:269.34tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate is a high quality and versatile chemical reagent that has been widely used in the synthesis of complex compounds. It is an intermediate for the production of fine chemicals and speciality chemicals. It can be used as a building block for various chemical reactions because it is a versatile building block with many functional groups that are reactive under different conditions.
Fórmula:C14H23NO4Pureza:Min. 98.0 Area-%Peso molecular:269.34 g/mol
![1,1-Dimethylethyl 2-[(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0400.37-0025.jpg&w=3840&q=75)
